Literature DB >> 7199182

Ethanol intoxication as a function of genotype dependent responses in three inbred mice strains.

S F Elston, K Blum, L DeLallo, A H Briggs.   

Abstract

Three strains of mice, ICR Swiss, DBA/2J and C57Bl/6J were compared for initial sensitivity, recovery from intoxication, and acute tolerance development to ethanol. The The C57Bl/6J mice were found to be less sensitive and to recover more rapidly from the effects of the same dose of ethanol than the other two strains treated. None of the strains tested demonstrated acute tolerance to ethanol when given the same dose 3 hours later.

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Year:  1982        PMID： 7199182     DOI： 10.1016/0091-3057(82)90005-3

Source DB:  PubMed          Journal:  Pharmacol Biochem Behav        ISSN： 0091-3057            Impact factor:   3.533


  2 in total

1.  Strain-Dependent Effects of Acute Alcohol on Synaptic Vesicle Recycling and Post-Tetanic Potentiation in Medial Glutamate Inputs to the Mouse Basolateral Amygdala.

Authors:  Dominic A Gioia; Brian McCool
Journal:  Alcohol Clin Exp Res       Date:  2017-02-18       Impact factor: 3.455

2.  Americas' opioid/psychostimulant epidemic would benefit from general population early identification of genetic addiction risk especially in children of alcoholics (COAs).

Authors:  K Blum; D Baron; M Hauser; S Henriksen; P K Thanos; C Black; D Siwicki; E J Modestino; B W Downs; S Badgaiyan; T A Simpatico; B Boyett; R D Badgaiyan
Journal:  J Syst Integr Neurosci       Date:  2019-10-31
  2 in total

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