Literature DB >> 7197567

The mechanism of the antagonism by naloxone of acute alcohol intoxication.

A A Badawy, M Evans.   

Abstract

Naloxone lowers blood-ethanol concentration and causes a simultaneous reversal of the disturbances in the redox states of the hepatic nicotinamide-adenine dinucleotide (phosphate) couples in acutely-ethanol-intoxicated rats. It is suggested that these effects of naloxone form the basis of its antagonism of acute alcohol intoxication.

Entities:  

Mesh：

Substances：

Year:  1981        PMID： 7197567      PMCID： PMC2071755          DOI： 10.1111/j.1476-5381.1981.tb10458.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  11 in total

1.  The effects of ethanol on tryptophan pyrrolase activity and their comparison with those of phenobarbitone and morphine.

Authors:  A A Badawy; M Evans
Journal:  Adv Exp Med Biol       Date:  1975       Impact factor: 2.622

2.  The effects of acute and chronic nicotine hydrogen (+)-tartrate administration and subsequent withdrawal on rat liver tryptophan pyrrolase activity and their comparison with those of morphine, phenobarbitone and ethanol.

Authors:  A A Badawy; M Evans
Journal:  Biochem J       Date:  1975-06       Impact factor: 3.857

3.  Reversal of ethanol-induced coma with naloxone.

Authors:  D B Jefferys; R J Flanagan; G N Volans
Journal:  Lancet       Date:  1980-02-09       Impact factor: 79.321

4.  Plasma ethanol, endorphin, and glucose experiment.

Authors:  C D Kimball; S M Huang; C E Torget; J C Houck
Journal:  Lancet       Date:  1980-08-23       Impact factor: 79.321

5.  Naloxone-induced inhibition of ethanol dependence in mice.

Authors:  K Blum; S Futterman; J E Wallace; H A Schwertner
Journal:  Nature       Date:  1977-01-06       Impact factor: 49.962

6.  The role of liver tryptophan pyrrolase in the opposite effects of chronic administration and subsequent withdrawal of drugs of dependence on rat brain tryptophan metabolism.

Authors:  A A Badawy; N F Punjani; M Evans
Journal:  Biochem J       Date:  1981-04-15       Impact factor: 3.857

7.  The metabolism of alcohol.

Authors:  A A Badawy
Journal:  Clin Endocrinol Metab       Date:  1978-07

8.  An assay procedure for nicotinamide-adenine dinucleotides in rat liver and other tissues.

Authors:  T F Slater; B Sawyer; U Sträuli
Journal:  Arch Int Physiol Biochim       Date:  1964-06

9.  Reversal by naloxone of the effects of chronic administration of drugs of dependence on rat liver and brain tryptophan metabolism.

Authors:  A A Badawy; M Evans; N F Punjani
Journal:  Br J Pharmacol       Date:  1981-10       Impact factor: 8.739

10.  Prevention by pyrazole of the effects of chronic ethanol administration on the redox states of the hepatic nicotinamide--adenine dinucleotide (phosphate) couples and on liver and brain tryptophan metabolism in the rat.

Authors:  N F Punjani; A A Badawy; M Evans
Journal:  Biochem J       Date:  1979-10-15       Impact factor: 3.857
View more
  4 in total

1.  Antagonism of the stimulant and depressant effects of ethanol in rats by naloxone.

Authors:  M Prunell; J Boada; M Feria; M A Benitez
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

2.  Nicotinamide Adenine Dinucleotide (NAD+) and Enkephalinase Inhibition (IV1114589NAD) Infusions Significantly Attenuate Psychiatric Burden Sequalae in Substance Use Disorder (SUD) in Fifty Cases.

Authors:  Kenneth Blum; David Han; David Baron; Shan Kazmi; Igor Elman; Luis Llanos Gomez; Marjorie C Gondre-Lewis; Panyotis K Thanos; Eric R Braverman; Rajendra D Badgaiyan
Journal:  Curr Psychiatry Res Rev       Date:  2022-06-21

3.  Antagonism of the behavioral effects of ethanol by naltrexone in BALB/c, C57BL/6, and DBA/2 mice.

Authors:  K Kiianmaa; P L Hoffman; B Tabakoff
Journal:  Psychopharmacology (Berl)       Date:  1983       Impact factor: 4.530

4.  Neonatal acute ethanol intoxication during the epidemic of COVID-19: a case report.

Authors:  Chao Sun; Yanyan Nie; Xiaoyu Cui; Fang Zhang; Yang Liu
Journal:  BMC Pediatr       Date:  2022-01-20       Impact factor: 2.125
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.