Literature DB >> 43138

Prevention by pyrazole of the effects of chronic ethanol administration on the redox states of the hepatic nicotinamide--adenine dinucleotide (phosphate) couples and on liver and brain tryptophan metabolism in the rat.

N F Punjani, A A Badawy, M Evans.   

Abstract

Chronic administration of pyrazole in the diet of rats does not cause toxicity and prevents the chronic effects of ethanol on: (1) the redox states of the hepatic NAD(P) couples; (2) liver tryptophan pyrrolase activity; (3) brain tryptophan and 5-hydroxytryptamine metabolism.

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Year:  1979        PMID： 43138      PMCID： PMC1161687          DOI： 10.1042/bj1840165

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  12 in total

1.  The effects of ethanol on tryptophan pyrrolase activity and their comparison with those of phenobarbitone and morphine.

Authors:  A A Badawy; M Evans
Journal:  Adv Exp Med Biol       Date:  1975       Impact factor: 2.622

2.  Regulation of rat liver tryptophan pyrrolase by its cofactor haem: Experiments with haematin and 5-aminolaevulinate and comparison with the substrate and hormonal mechanisms.

Authors:  A A Badawy; M Evans
Journal:  Biochem J       Date:  1975-09       Impact factor: 3.857

3.  Effects of pyrazole on rat liver tryptophan oxygenase.

Authors:  H Rouach; C Ribière; J Nordmann; R Nordmann
Journal:  Life Sci       Date:  1976-08-15       Impact factor: 5.037

4.  Pyrazole and induction of fatty liver by a single dose of ethanol.

Authors:  G O Bustos; H Kalant; J M Khanna; J Loth
Journal:  Science       Date:  1970-06-26       Impact factor: 47.728

5.  Effect of chronic intake of ethanol on pyridine nucleotide levels in rat liver and kidney.

Authors:  H Kalant; J M Khanna; J Loth
Journal:  Can J Physiol Pharmacol       Date:  1970-08       Impact factor: 2.273

6.  Effect of pyrazole on the induction of fatty liver by chronic administration of ethanol.

Authors:  H Kalant; J M Khanna; G O Bustos
Journal:  Biochem Pharmacol       Date:  1972-03-15       Impact factor: 5.858

7.  Liver cell necrosis in rats after prolonged ethanol ingestion under the influence of an alcohol-dehydrogenase inhibitor.

Authors:  W K Lelbach
Journal:  Experientia       Date:  1969-08-15

8.  Effect of pyrazoles and other compounds on alcohol metabolism.

Authors:  D Lester; W Z Keokosky; F Felzenberg
Journal:  Q J Stud Alcohol       Date:  1968-06

9.  An assay procedure for nicotinamide-adenine dinucleotides in rat liver and other tissues.

Authors:  T F Slater; B Sawyer; U Sträuli
Journal:  Arch Int Physiol Biochim       Date:  1964-06

10.  Liver tryptophan pyrrolase and brain 5-hydroxytryptamine: effects of chronic ethanol administration.

Authors:  A A Badawy; N F Punjani; M Evans
Journal:  Biochem Soc Trans       Date:  1978       Impact factor: 5.407
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  6 in total

1.  The role of liver tryptophan pyrrolase in the opposite effects of chronic administration and subsequent withdrawal of drugs of dependence on rat brain tryptophan metabolism.

Authors:  A A Badawy; N F Punjani; M Evans
Journal:  Biochem J       Date:  1981-04-15       Impact factor: 3.857

2.  Reversal by naloxone of the effects of chronic administration of drugs of dependence on rat liver and brain tryptophan metabolism.

Authors:  A A Badawy; M Evans; N F Punjani
Journal:  Br J Pharmacol       Date:  1981-10       Impact factor: 8.739

3.  Inhibition of rat brain tryptophan metabolism by ethanol withdrawal and possible involvement of the enhanced liver tryptophan pyrrolase activity.

Authors:  A A Badawy; N F Punjani; C M Evans; M Evans
Journal:  Biochem J       Date:  1980-11-15       Impact factor: 3.857

4.  The mechanism of the antagonism by naloxone of acute alcohol intoxication.

Authors:  A A Badawy; M Evans
Journal:  Br J Pharmacol       Date:  1981-11       Impact factor: 8.739

5.  Possible involvement of the enhanced tryptophan pyrrolase activity in the corticosterone- and starvation-induced increases in concentrations of nicotinamide-adenine dinucleotides (phosphates) in rat liver.

Authors:  A A Badawy
Journal:  Biochem J       Date:  1981-04-15       Impact factor: 3.857

Review 6.  Immunotherapy of COVID-19 with poly (ADP-ribose) polymerase inhibitors: starting with nicotinamide.

Authors:  Abdulla A-B Badawy
Journal:  Biosci Rep       Date:  2020-10-30       Impact factor: 3.840
  6 in total

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