Literature DB >> 7196001

Anatomical correlates of morphine-withdrawal syndrome: differential participation of structures located within the limbic system and striatum.

E C Tremblay, G Charton.   

Abstract

Morphine-withdrawal signs have been induced, in morphine-dependent rats, by microinjection of naloxone in various diencephalic and telencephalic structures. A differential participation of the central amygdala, lateral septum, dorsal hippocampus, medial thalamic nuclei, globus pallidus and caudateputamen has been observed for the following signs: jumping, wet-dog shakes, paw tremor, chewing and diarrhea. Amygdala, medial thalamus and globus pallidus were the most sensitive to local injection of naloxone.

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Year:  1981        PMID： 7196001     DOI： 10.1016/0304-3940(81)90030-6

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  9 in total

1.  A Novel Mu-Delta Opioid Agonist Demonstrates Enhanced Efficacy With Reduced Tolerance and Dependence in Mouse Neuropathic Pain Models.

Authors:  Wei Lei; Rakesh H Vekariya; Subramaniam Ananthan; John M Streicher
Journal:  J Pain       Date:  2019-06-12       Impact factor: 5.820

2.  Involvement of cyclic AMP systems in morphine physical dependence in mice: prevention of development of morphine dependence by rolipram, a phosphodiesterase 4 inhibitor.

Authors:  T Mamiya; Y Noda; X Ren; M Hamdy; S Furukawa; T Kameyama; K Yamada; T Nabeshima
Journal:  Br J Pharmacol       Date:  2001-03       Impact factor: 8.739

3.  In vivo tracer studies of glucose metabolism, cerebral blood flow, and protein synthesis in naloxone precipitated morphine withdrawal.

Authors:  W A Geary; G F Wooten
Journal:  Neurochem Res       Date:  1987-07       Impact factor: 3.996

4.  From mouse to man: the 5-HT3 receptor modulates physical dependence on opioid narcotics.

Authors:  Larry F Chu; De-Yong Liang; Xiangqi Li; Peyman Sahbaie; Nicole D'arcy; Guochun Liao; Gary Peltz; J David Clark
Journal:  Pharmacogenet Genomics       Date:  2009-03       Impact factor: 2.089

5.  Evidence that 5-hydroxytryptamine in the forebrain is involved in naloxone-precipitated jumping in morphine-dependent rats.

Authors:  L Cervo; S Romandini; R Samanin
Journal:  Br J Pharmacol       Date:  1983-08       Impact factor: 8.739

6.  Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast).

Authors:  Mark R Hutchinson; Susannah S Lewis; Benjamen D Coats; David A Skyba; Nicole Y Crysdale; Debra L Berkelhammer; Anita Brzeski; Alexis Northcutt; Christine M Vietz; Charles M Judd; Steven F Maier; Linda R Watkins; Kirk W Johnson
Journal:  Brain Behav Immun       Date:  2008-10-04       Impact factor: 7.217

7.  Suppression of naloxone-precipitated withdrawal jumps in morphine-dependent mice by stimulation of prostaglandin EP3 receptor.

Authors:  T Nakagawa; M Minami; S Katsumata; Y Ienaga; M Satoh
Journal:  Br J Pharmacol       Date:  1995-11       Impact factor: 8.739

8.  Anterior cingulate cortex and its projections to the ventral tegmental area regulate opioid withdrawal, the formation of opioid context associations and context-induced drug seeking.

Authors:  Greer McKendrick; Dillon S McDevitt; Peter Shafeek; Adam Cottrill; Nicholas M Graziane
Journal:  Front Neurosci       Date:  2022-08-05       Impact factor: 5.152

9.  Anterior cingulate cortex is necessary for spontaneous opioid withdrawal and withdrawal-induced hyperalgesia in male mice.

Authors:  Dillon S McDevitt; Greer McKendrick; Nicholas M Graziane
Journal:  Neuropsychopharmacology       Date:  2021-08-02       Impact factor: 8.294
  9 in total

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