Literature DB >> 7189093

On the heritability of serum high density lipoprotein in twins.

P Sistonen, C Ehnholm.   

Abstract

To estimate the relative contributions of hereditary vs. environmental factors in the variation of high density lipoprotein, we measured the concentrations of its main apoprotein components, apoprotein A-I (apo A-I) and apoprotein A-II (apo A-II), in serum samples from 65 monozygotic (MZ) and 70 dizygotic (DZ) like-sexed twin pairs. Evidence for a genetic component of variance was found for apo A-II, giving heritability (h2) estimates of .35 and .30 for males and females, respectively. No genetic contribution to the variance of apo A-I could be demonstrated. Additionally, males had lower concentrations of apo A-I, but higher of apo A-II, than females.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 7189093      PMCID： PMC1685926     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  17 in total

Review 1.  Lipoprotein metabolism.

Authors:  S Eisenberg; R I Levy
Journal:  Adv Lipid Res       Date:  1975

2.  Sampling variances in twin and sibling studies of man.

Authors:  K W Kang; J P Lindemann; J C Christian; W E Nance; J A Norton
Journal:  Hum Hered       Date:  1974       Impact factor: 0.444

3.  Choice of an estimate of genetic variance from twin data.

Authors:  J C Christian; K W Kang; J J Norton
Journal:  Am J Hum Genet       Date:  1974-03       Impact factor: 11.025

4.  Plasma-high-density-lipoprotein concentration and development of ischaemic heart-disease.

Authors:  G J Miller; N E Miller
Journal:  Lancet       Date:  1975-01-04       Impact factor: 79.321

5.  Quantitation of apolipoprotein A-I of human plasma high density lipoprotein.

Authors:  J J Albers; P W Wahl; V G Cabana; W R Hazzard; J J Hoover
Journal:  Metabolism       Date:  1976-06       Impact factor: 8.694

6.  Serum-high-density-lipoprotein and atherosclerotic heart-disease.

Authors:  K Berg; A L Borresen
Journal:  Lancet       Date:  1976-03-06       Impact factor: 79.321

7.  The measurement of apolipoprotein A-I and A-II levels in men and women by immunoassay.

Authors:  M C Cheung; J J Albers
Journal:  J Clin Invest       Date:  1977-07       Impact factor: 14.808

8.  HDL cholesterol and other lipids in coronary heart disease. The cooperative lipoprotein phenotyping study.

Authors:  W P Castelli; J T Doyle; T Gordon; C G Hames; M C Hjortland; S B Hulley; A Kagan; W J Zukel
Journal:  Circulation       Date:  1977-05       Impact factor: 29.690

9.  Effects of chorion type on variation in cord blood cholesterol of monozygotic twins.

Authors:  L A Corey; K W Kang; J C Christian; J A Norton; R E Harris; W E Nance
Journal:  Am J Hum Genet       Date:  1976-09       Impact factor: 11.025

10.  The Tromsø heart-study. High-density lipoprotein and coronary heart-disease: a prospective case-control study.

Authors:  N E Miller; D S Thelle; O H Forde; O D Mjos
Journal:  Lancet       Date:  1977-05-07       Impact factor: 79.321
View more
  7 in total

1.  Genetic analysis of apolipoprotein A-I in two dietary environments.

Authors:  J Blangero; J W MacCluer; C M Kammerer; G E Mott; T D Dyer; H C McGill
Journal:  Am J Hum Genet       Date:  1990-09       Impact factor: 11.025

2.  The genetic determination of plasma apolipoprotein A-I levels measured by radioimmunoassay: a study of high-risk pedigrees.

Authors:  P P Moll; C F Sing; R R Williams; S J Mao; B A Kottke
Journal:  Am J Hum Genet       Date:  1986-03       Impact factor: 11.025

3.  Biliary lipid composition in monozygotic and dizygotic pairs of twins.

Authors:  Y Antero Kesäniemi; M Koskenvuo; M Vuoristo; T A Miettinen
Journal:  Gut       Date:  1989-12       Impact factor: 23.059

4.  Genome-wide linkage scans for loci affecting total cholesterol, HDL-C, and triglycerides: the Family Blood Pressure Program.

Authors:  Suzette J Bielinski; Weihong Tang; James S Pankow; Michael B Miller; Thomas H Mosley; Eric Boerwinkle; Richard A Olshen; J David Curb; Cashell E Jaquish; D C Rao; Alan Weder; Donna K Arnett
Journal:  Hum Genet       Date:  2006-07-26       Impact factor: 4.132

5.  Genetic determination of plasma apolipoprotein AI in a population-based sample.

Authors:  P P Moll; V V Michels; W H Weidman; B A Kottke
Journal:  Am J Hum Genet       Date:  1989-01       Impact factor: 11.025

6.  Segregation analysis of apolipoprotein A1 levels in families of adolescents: a community-based study in Taiwan.

Authors:  Kuo-Liong Chien; Wei J Chen; Hsiu-Ching Hsu; Ta-Chen Su; Ming-Fong Chen; Yuan-Teh Lee
Journal:  BMC Genet       Date:  2006-01-20       Impact factor: 2.797

7.  Heritability of serum apolipoprotein concentrations in middle-aged Japanese twins.

Authors:  Yang Ping Cai; Kazuo Hayakawa; Reiko Nishihara; Kenji Kato
Journal:  J Epidemiol       Date:  2009-08-22       Impact factor: 3.211
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.