Literature DB >> 7185044

Catalytic mechanism of histone in peptide formation from phenylalanyl adenylate.

N Yamamoto, M Ishigami, M Kinjo.   

Abstract

Catalytic action of histone on peptide formation from phenylalanyl adenylate was studied. A peptide bond formation from phenylalanyl adenylate releases two protons. The proton release was increased in the presence of histone at a higher concentration. The catalytic action seems to be due to basic circumstance induced by histone, since (1) basic condition enhanced the proton release; (2) basic amino acid did not enhance the proton release.

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Year:  1982        PMID: 7185044     DOI: 10.1007/bf00927067

Source DB:  PubMed          Journal:  Orig Life        ISSN: 0302-1688


  4 in total

1.  The chemical synthesis of amino acyladenylates.

Authors:  P BERG
Journal:  J Biol Chem       Date:  1958-09       Impact factor: 5.157

2.  Selective condensation of aminoacyl adenylates by nucleoproteinoid microparticles (prebiotic-lysine-model system-genetic code).

Authors:  T Nakashima; S W Fox
Journal:  Proc Natl Acad Sci U S A       Date:  1972-01       Impact factor: 11.205

3.  Effect of polynucleotides and a basic protein on the condensation of phenylalanyl adenylate.

Authors:  M Ishigami; N Tonotsuka-Ohta; K Nagano; M Kinjo
Journal:  Orig Life       Date:  1980-09

4.  Synthesis of peptides from amino acids and ATP with lysine-rich proteinoid.

Authors:  T Nakashima; S W Fox
Journal:  J Mol Evol       Date:  1980-05       Impact factor: 2.395

  4 in total

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