Literature DB >> 716888

Reliability of histo-pathological diagnosis of squamous epithelial changes of the uterine cervix.

J Ringsted, F Amtrup, C Asklund, P Baunsgaard, H E Christensen, L Hansen, C Jakobsen, K Jensen, J Moesner, J Rasmussen, I Reintoft, J Rolschau, H Starklint, N Thommesen, J Vrang.   

Abstract

The reliability of histological diagnosis of squamous epithelial changes was tested by letting 13 pathologists read 1,001 consecutive cervical biopsies twice. Intra-observer and inter-observer agreement, variance, and deviation of diagnosis were determined. The diagnostic ability showed great individual variation and no significant correlation to experience in pathology. The diagnosis of invasive cancer had a high diagnostic specificity, and the diagnostic sensitivity of the diagnosis of no significant epithelial changes was high too. The reliability of the diagnosis of dysplasia and carcinoma in situ proved unsatisfactory.

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Year:  1978        PMID: 716888     DOI: 10.1111/j.1699-0463.1978.tb02043.x

Source DB:  PubMed          Journal:  Acta Pathol Microbiol Scand A        ISSN: 0365-4184


  7 in total

1.  Visualising scanning patterns of pathologists in the grading of cervical intraepithelial neoplasia.

Authors:  E S M Tiersma; A A W Peters; H A Mooij; G J Fleuren
Journal:  J Clin Pathol       Date:  2003-09       Impact factor: 3.411

2.  Image analysis combined with quantitative cytochemistry. Results and instrumental developments for cancer diagnosis.

Authors:  J S Ploem; A M van Driel-Kulker; L Goyarts-Veldstra; J J Ploem-Zaaijer; N P Verwoerd; M van der Zwan
Journal:  Histochemistry       Date:  1986

3.  Observer variability in histopathological reporting of cervical biopsy specimens.

Authors:  A J Robertson; J M Anderson; J S Beck; R A Burnett; S R Howatson; F D Lee; A M Lessells; K M McLaren; S M Moss; J G Simpson
Journal:  J Clin Pathol       Date:  1989-03       Impact factor: 3.411

4.  Quality assurance and medical audit in histopathology.

Authors:  B C Morson
Journal:  J Clin Pathol       Date:  1983-10       Impact factor: 3.411

5.  External quality assessment of clinical laboratories in the United Kingdom.

Authors:  T P Whitehead; F P Woodford
Journal:  J Clin Pathol       Date:  1981-09       Impact factor: 3.411

6.  Stereological estimates of nuclear volume in squamous cell carcinoma of the uterine cervix and its precursors.

Authors:  F B Sørensen; P Bichel; A Jakobsen
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1991

7.  Histochemical investigation of cervical intraepithelial neoplasia.

Authors:  B Nilson; B Andersch; G Hansson; G Heyden
Journal:  Arch Gynecol       Date:  1987
  7 in total

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