Literature DB >> 7166528

AM-2604 A, a new antiviral antibiotic produced by a strain of Streptomyces.

S Omura, H Shimizu, Y Iwai, K Hinotozawa, K Otoguro, H Hashimoto, A Nakagawa.   

Abstract

A novel antibiotic, AM-2604 A was isolated from the fermentation broth of Streptomyces sp. AM-2604 by solvent extraction and silica gel column chromatography. The antibiotic is pale yellow needles possessing UV absorption maxima at 280 nm and 330 nm (sh). The antibiotic possesses weak activity against fungi and trichomonad and potent inhibitory activity against various RNA and DNA viruses in vitro.

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Year:  1982        PMID: 7166528     DOI: 10.7164/antibiotics.35.1632

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  3 in total

Review 1.  Philosophy of new drug discovery.

Authors:  S Omura
Journal:  Microbiol Rev       Date:  1986-09

2.  Hyaluromycin, a new hyaluronidase inhibitor of polyketide origin from marine Streptomyces sp.

Authors:  Enjuro Harunari; Chiaki Imada; Yasuhiro Igarashi; Takao Fukuda; Takeshi Terahara; Takeshi Kobayashi
Journal:  Mar Drugs       Date:  2014-01-21       Impact factor: 5.118

3.  The virulome of Streptomyces scabiei in response to cello-oligosaccharide elicitors.

Authors:  Benoit Deflandre; Nudzejma Stulanovic; Sören Planckaert; Sinaeda Anderssen; Beatrice Bonometti; Latifa Karim; Wouter Coppieters; Bart Devreese; Sébastien Rigali
Journal:  Microb Genom       Date:  2022-01
  3 in total

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