Literature DB >> 7166025

A quantitative antiglobulin test for IgG for use in blood transfusion serology.

A H Merry, E E Thomson, V I Rawlinson, F Stratton.   

Abstract

A sensitive method has been developed using 125I-labelled anti-IgG which allows detection of IgG present on the red cell surface. By suitable absorption and correction for non-specific binding to trypsinized red cells, a reproducible, accurate method of quantitating IgG absorbed onto red cells is obtained. The number of IgG molecules present on normal cells was found to range from 5 to 90 with an average of 39. Studies of correlation of agglutination in the antiglobulin test with numbers of IgG molecules on the cell were also undertaken.

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Year:  1982        PMID: 7166025     DOI: 10.1111/j.1365-2257.1982.tb00483.x

Source DB:  PubMed          Journal:  Clin Lab Haematol        ISSN: 0141-9854


  9 in total

1.  Kinetic analysis of the blood clearance and organ uptake curves of IgG-coated red cells in HLA-typed controls and patients with Wegener's granulomatosis.

Authors:  F J van der Woude; H Beekhuis; J M Beelen; T H The
Journal:  Eur J Nucl Med       Date:  1986

2.  Small quantities of erythrocyte bound immunoglobulins and autoimmune haemolysis.

Authors:  R J Sokol; S Hewitt; D J Booker; R Stamps
Journal:  J Clin Pathol       Date:  1987-03       Impact factor: 3.411

3.  Mononuclear phagocyte system Fc-receptor function in patients with seropositive rheumatoid arthritis.

Authors:  S Lobatto; F C Breedveld; J A Camps; E K Pauwels; M L Westedt; M R Daha; L A van Es
Journal:  Clin Exp Immunol       Date:  1987-03       Impact factor: 4.330

4.  Utilisation of Flow-cytometry in the Diagnosis of Auto Immune Haemolytic Anaemia.

Authors:  Jitender Mohan Khunger; H P Pati; M Mahapatra; Arjun Khunger
Journal:  Indian J Hematol Blood Transfus       Date:  2018-10-05       Impact factor: 0.900

5.  Passive haemagglutination inhibition for quantitation of red cell associated IgG.

Authors:  H I Atrah; J G Templeton; R J Crawford; G S Gabra; R Mitchell
Journal:  J Clin Pathol       Date:  1987-05       Impact factor: 3.411

6.  Natural autoantibodies may play a role in ineffective erythropoiesis during megaloblastic haemopoiesis.

Authors:  E Wiener; S N Wickramasinghe
Journal:  Clin Exp Immunol       Date:  1991-01       Impact factor: 4.330

7.  Reaction of rheumatoid factors with IgG3 monoclonal anti-Rh(D) antibodies: more frequent reactivity to a monoclonal antibody of the Gm allotype G3m(5) in rheumatoid patients negative for G3m(5).

Authors:  A H Puttick; E A Williamson; A H Merry; B M Kumpel; K M Thompson; V E Jones
Journal:  Ann Rheum Dis       Date:  1988-11       Impact factor: 19.103

8.  Enzyme linked direct antiglobulin tests in patients with autoimmune haemolysis.

Authors:  R J Sokol; S Hewitt; D J Booker; R Stamps
Journal:  J Clin Pathol       Date:  1985-08       Impact factor: 3.411

9.  Surface antigen expression on Plasmodium falciparum-infected erythrocytes is modified in alpha- and beta-thalassemia.

Authors:  G A Luzzi; A H Merry; C I Newbold; K Marsh; G Pasvol; D J Weatherall
Journal:  J Exp Med       Date:  1991-04-01       Impact factor: 14.307

  9 in total

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