| Literature DB >> 7166025 |
A H Merry, E E Thomson, V I Rawlinson, F Stratton.
Abstract
A sensitive method has been developed using 125I-labelled anti-IgG which allows detection of IgG present on the red cell surface. By suitable absorption and correction for non-specific binding to trypsinized red cells, a reproducible, accurate method of quantitating IgG absorbed onto red cells is obtained. The number of IgG molecules present on normal cells was found to range from 5 to 90 with an average of 39. Studies of correlation of agglutination in the antiglobulin test with numbers of IgG molecules on the cell were also undertaken.Mesh:
Substances:
Year: 1982 PMID: 7166025 DOI: 10.1111/j.1365-2257.1982.tb00483.x
Source DB: PubMed Journal: Clin Lab Haematol ISSN: 0141-9854