Literature DB >> 7165351

Microenema of 8-methoxypsoralen in photochemotherapy of psoriasis.

A H Siddiqui, L Stolk, H R Korthals Altes-Levij van Vinninghe, A Kammeijer, R H Cormane.   

Abstract

Reasonably high plasma levels were obtained 1/2 h after 8-methoxypsoralen (8-MOP) administration by microenema. This method was used in photochemotherapy of psoriasis and reasonably good clinical results with no serious side effects were obtained. The advantages of this modality include noninvolvement of the upper gastrointestinal tract, high bioavailability of psoralen, peak levels at a predictable time, and rapid elimination of the drug.

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Year:  1982        PMID: 7165351     DOI: 10.1007/bf00409249

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN: 0340-3696            Impact factor:   3.017


  13 in total

1.  Phototesting and dosimetry for photochemotherapy.

Authors:  K Wolff; F Gschnait; H Hönigsmann; K Konrad; J A Parrish; T B Fitzpatrick
Journal:  Br J Dermatol       Date:  1977-01       Impact factor: 9.302

2.  Photochemotherapy of psoriasis with oral methoxsalen and longwave ultraviolet light.

Authors:  J A Parrish; T B Fitzpatrick; L Tanenbaum; M A Pathak
Journal:  N Engl J Med       Date:  1974-12-05       Impact factor: 91.245

3.  Oral dosage in methoxsalen phototoxicity.

Authors:  A M Kligman; F P Goldstein
Journal:  Arch Dermatol       Date:  1973-04

4.  8-Methoxypsoralen-gas chromatographic determination and serum kinetics.

Authors:  J Gazith; W Schalla; H Schaefer
Journal:  Arch Dermatol Res       Date:  1978-11-10       Impact factor: 3.017

5.  8-MOP plasma levels in PUVA problem cases with psoriasis.

Authors:  G Wagner; C Hofmann; U Busch; J Schmid; G Plewig
Journal:  Br J Dermatol       Date:  1979-09       Impact factor: 9.302

6.  Initial photochemotherapy of psoriasis with orally administered 8-methoxypsoralen and longwave ultraviolet light (PUVA).

Authors:  A H Siddiqui; R H Cormane
Journal:  Br J Dermatol       Date:  1979-03       Impact factor: 9.302

7.  Pharmacokinetics and metabolite-pattern of 8-methoxypsoralen in man following oral administration as compared to the pharmacokinetics in rat and dog.

Authors:  U Busch; J Schmid; F W Koss; H Zipp; A Zimmer
Journal:  Arch Dermatol Res       Date:  1978-08-28       Impact factor: 3.017

8.  Plasma levels of 8-methoxypsoralen and phototoxicity studies during PUVA treatment of psoriasis with meladinin tablets.

Authors:  P Thune
Journal:  Acta Derm Venereol       Date:  1978       Impact factor: 4.437

9.  Photochemotherapy of psoriasis with relevance to 8-methoxypsoralen plasma level and low intensity irradiation.

Authors:  P Thune; G Volden
Journal:  Acta Derm Venereol       Date:  1977       Impact factor: 4.437

10.  Serum and saliva levels of 8-methoxypsoralen after rectal administration as a micro-enema.

Authors:  L Stolk; A H Siddiqui; A Kammeyer; R H Cormane; P A van Zwieten
Journal:  Br J Dermatol       Date:  1981-04       Impact factor: 9.302

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  2 in total

1.  Comparison of serum levels and clinical results of PUVA therapy with three different dosage forms of 8-methoxypsoralen.

Authors:  A H Siddiqui; L M Stolk; R H Cormane
Journal:  Arch Dermatol Res       Date:  1984       Impact factor: 3.017

Review 2.  Clinical pharmacokinetics of methoxsalen and other psoralens.

Authors:  F A de Wolff; T V Thomas
Journal:  Clin Pharmacokinet       Date:  1986 Jan-Feb       Impact factor: 6.447

  2 in total

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