Literature DB >> 7159089

Fungal transformations of triparanol.

S A Warner, G W Sovocool, A J Domnas.   

Abstract

Fungal transformations of triparanol, a hypercholesterolemic drug, were studied in Lagenidium giganteum and Lagenidium callinectes. The products were identified by combined gas chromatography-mass spectrometry. Two metabolites were observed from each organism; only one of the metabolites was found in both organisms.

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Year:  1982        PMID： 7159089      PMCID： PMC242214          DOI： 10.1128/aem.44.6.1471-1475.1982

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  4 in total

1.  Studies of cholesterol biosynthesis. I. The identification of desmosterol in serum and tissues of animals and man treated with MER-29.

Authors:  J AVIGAN; D STEINBERG; H E VROMAN; M J THOMPSON; E MOSETTIG
Journal:  J Biol Chem       Date:  1960-11       Impact factor: 5.157

2.  THE CROSS-LINKS IN RESILIN IDENTIFIED AS DITYROSINE AND TRITYROSINE.

Authors:  S O ANDERSEN
Journal:  Biochim Biophys Acta       Date:  1964-10-09

3.  Effects of triparanol and AY-9944 upon sterol biosynthesis in Chorella.

Authors:  G W Patterson; P J Doyle; L G Dickson; J T Chan
Journal:  Lipids       Date:  1974-08       Impact factor: 1.880

4.  Conversion of beta sitosterol to cholesterol blocked in an insect by hypocholesterolemic agents.

Authors:  J A Svoboda; W E Robbins
Journal:  Science       Date:  1967-06-23       Impact factor: 47.728
  4 in total

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