Literature DB >> 7159069

Pharmacokinetics of cefadroxil and cefaclor during an eight-day dosage period.

B Hampel, H Lode, J Wagner, P Koeppe.   

Abstract

The concentrations of cefadroxil and cefaclor in serum were studied in eight healthy volunteers receiving 1,000 mg of both substances three times per day for 8 days. Intraindividual comparisons showed an increase in peak serum levels of cefadroxil from days 1 to 8 in seven of eight volunteers. Cefaclor peak concentrations did not rise during the 8 days.

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Year:  1982        PMID： 7159069      PMCID： PMC185721          DOI： 10.1128/AAC.22.6.1061

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  3 in total

1.  Comparative pharmacokinetics of cephalexin, cefaclor, cefadroxil, and CGP 9000.

Authors:  H Lode; R Stahlmann; P Koeppe
Journal:  Antimicrob Agents Chemother       Date:  1979-07       Impact factor: 5.191

2.  Pharmacological evaluation of cefaclor in volunteers.

Authors:  G R Hodges; C Liu; D R Hinthorn; J L Harms; D L Dworzack
Journal:  Antimicrob Agents Chemother       Date:  1978-09       Impact factor: 5.191

3.  Pharmacologic studies with cefaclor, a new oral cephalosporin.

Authors:  B R Meyers; S Z Hirschman; G Wormser; G Gartenberg; E Srulevitch
Journal:  J Clin Pharmacol       Date:  1978-04       Impact factor: 3.126
  3 in total
  3 in total

1.  Pharmacokinetics of cefuroxime axetil and cefaclor: relationship of concentrations in serum to MICs for common respiratory pathogens.

Authors:  N C James; K H Donn; J J Collins; I M Davis; T L Lloyd; R W Hart; J R Powell
Journal:  Antimicrob Agents Chemother       Date:  1991-09       Impact factor: 5.191

2.  Multiple-dose pharmacokinetics of cefprozil and its impact on intestinal flora of volunteers.

Authors:  H Lode; C Müller; K Borner; C E Nord; P Koeppe
Journal:  Antimicrob Agents Chemother       Date:  1992-01       Impact factor: 5.191

3.  Concentrations of phenoxymethylpenicillin and cefadroxil in tonsillar tissue and tonsillar surface fluid.

Authors:  A Strömberg; U Friberg; O Cars
Journal:  Eur J Clin Microbiol       Date:  1987-10       Impact factor: 3.267
  3 in total

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