Literature DB >> 7157462

High-performance liquid chromatographic measurement of amiodarone and its desethyl metabolite: methodology and preliminary observations.

G C Storey, D W Holt, P Holt, P V Curry.   

Abstract

A high-performance liquid chromatographic technique is described for the measurement of amiodarone and its desethyl metabolite in plasma. Preliminary observations are presented on the concentrations of metabolite found during the early stages of chronic amiodarone therapy. A case history is outlined in which noncompliance during treatment with amiodarone was confirmed by measurement of the ratio of desethylamiodarone to amiodarone concentrations.

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 7157462     DOI： 10.1097/00007691-198212000-00009

Source DB:  PubMed          Journal:  Ther Drug Monit        ISSN： 0163-4356            Impact factor:   3.681


  8 in total

1.  Peripheral neutrophil inclusions in amiodarone treated patients.

Authors:  P C Adams; P Sloan; A R Morley; D W Holt
Journal:  Br J Clin Pharmacol       Date:  1986-12       Impact factor: 4.335

Review 2.  Risk-benefit assessment of amiodarone in the treatment of cardiac arrhythmias.

Authors:  P J Counihan; W J McKenna
Journal:  Drug Saf       Date:  1990 Jul-Aug       Impact factor: 5.606

3.  High-performance liquid chromatographic measurement of amiodarone and desethylamiodarone in small tissue samples after enzymatic digestion.

Authors:  G C Storey; P C Adams; R W Campbell; D W Holt
Journal:  J Clin Pathol       Date:  1983-07       Impact factor: 3.411

4.  Use of amiodarone during pregnancy.

Authors:  D J Robson; M V Jeeva Raj; G C Storey; D W Holt
Journal:  Postgrad Med J       Date:  1985-01       Impact factor: 2.401

5.  Pharmacokinetics of amiodarone, desethylamiodarone and other iodine-containing amiodarone metabolites.

Authors:  M Stäubli; A Troendle; B Schmid; P Balmer; B Kohler; H Studer; J Bircher
Journal:  Eur J Clin Pharmacol       Date:  1985       Impact factor: 2.953

6.  Peripheral neuropathy during longterm high-dose amiodarone therapy.

Authors:  A G Fraser; I N McQueen; A H Watt; M R Stephens
Journal:  J Neurol Neurosurg Psychiatry       Date:  1985-06       Impact factor: 10.154

7.  Intravenous and oral amiodarone for arrhythmias in children.

Authors:  C A Bucknall; B R Keeton; P V Curry; M J Tynan; G R Sutherland; D W Holt
Journal:  Br Heart J       Date:  1986-09

8.  The digoxin-amiodarone interaction.

Authors:  K Robinson; A Johnston; S Walker; J P Mulrow; W J McKenna; D W Holt
Journal:  Cardiovasc Drugs Ther       Date:  1989-03       Impact factor: 3.727
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.