Literature DB >> 2989436

Peripheral neuropathy during longterm high-dose amiodarone therapy.

A G Fraser, I N McQueen, A H Watt, M R Stephens.   

Abstract

Three patients developed peripheral neuropathy after taking amiodarone for more than 18 months. All had high serum concentrations of amiodarone and its desethyl metabolite; in one patient concentrations in a sural nerve biopsy were 80 times higher than in serum. Peripheral neuropathy is a complication of large doses of amiodarone taken over long periods.

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Year:  1985        PMID: 2989436      PMCID: PMC1028375          DOI: 10.1136/jnnp.48.6.576

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  15 in total

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Journal:  Schweiz Rundsch Med Prax       Date:  1976-09-14

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Journal:  Eur Neurol       Date:  1982 Jan-Feb       Impact factor: 1.710

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Journal:  Ther Drug Monit       Date:  1982       Impact factor: 3.681

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Journal:  J Neurol       Date:  1979-01-05       Impact factor: 4.849

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  3 in total

1.  Unusual amiodarone toxicity in a child.

Authors:  Bahram Kakavand; Thomas G Di Sessa
Journal:  J Pediatr Pharmacol Ther       Date:  2008-04

2.  Antiarrhythmic drugs and polyneuropathy. The Collaborative Group for the Study of Polyneuropathy.

Authors: 
Journal:  J Neurol Neurosurg Psychiatry       Date:  1994-03       Impact factor: 10.154

3.  Amiodarone Alters Cholesterol Biosynthesis through Tissue-Dependent Inhibition of Emopamil Binding Protein and Dehydrocholesterol Reductase 24.

Authors:  Luke B Allen; Thiago C Genaro-Mattos; Allison Anderson; Ned A Porter; Károly Mirnics; Zeljka Korade
Journal:  ACS Chem Neurosci       Date:  2020-04-29       Impact factor: 4.418

  3 in total

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