Literature DB >> 7157375

Covalent binding of a neurotoxic n-hexane metabolite: conversion of primary amines to substituted pyrrole adducts by 2,5-hexanedione.

A P DeCaprio, E J Olajos, P Weber.   

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Year:  1982        PMID: 7157375     DOI: 10.1016/0041-008x(82)90389-1

Source DB:  PubMed          Journal:  Toxicol Appl Pharmacol        ISSN: 0041-008X            Impact factor:   4.219


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  18 in total

Review 1.  Covalent modification of biological targets with natural products through Paal-Knorr pyrrole formation.

Authors:  Alexander Kornienko; James J La Clair
Journal:  Nat Prod Rep       Date:  2017-08-30       Impact factor: 13.423

2.  Spectrophotometric determination of pyrrole-like substances in urine of rat and man: an assay for the evaluation of 2,5-hexanedione formed from n-hexane.

Authors:  W Kessler; H Heilmaier; P Kreuzer; J H Shen; M Filser; J G Filser
Journal:  Arch Toxicol       Date:  1990       Impact factor: 5.153

Review 3.  Toxic neuropathies: Mechanistic insights based on a chemical perspective.

Authors:  Richard M LoPachin; Terrence Gavin
Journal:  Neurosci Lett       Date:  2014-09-16       Impact factor: 3.046

4.  Quantitative alterations of S-100 protein and neuron specific enolase in the rat nervous system after chronic 2,5-hexanedione exposure.

Authors:  J E Karlsson; S Wang; L E Rosengren; K G Haglid
Journal:  Neurochem Res       Date:  1993-02       Impact factor: 3.996

5.  Neurofilaments are nonessential to the pathogenesis of toxicant-induced axonal degeneration.

Authors:  J D Stone; A P Peterson; J Eyer; T G Oblak; D W Sickles
Journal:  J Neurosci       Date:  2001-04-01       Impact factor: 6.167

6.  Effects of vitamin B12 and B6 on 2,5-hexanedione-induced neuropathy.

Authors:  J Misumi; M Nagano; J Kaisaku; T Hitoshi
Journal:  Arch Toxicol       Date:  1985-01       Impact factor: 5.153

7.  Toxicokinetic study of pyrrole adducts and its potential application for biological monitoring of 2,5-hexanedione subacute exposure.

Authors:  Hong-Yin Yin; Ying Guo; Fu-Yong Song; Tao Zeng; Ke-Qin Xie
Journal:  Int Arch Occup Environ Health       Date:  2014-08       Impact factor: 3.015

8.  Molecular mechanism of glyceraldehyde-3-phosphate dehydrogenase inactivation by α,β-unsaturated carbonyl derivatives.

Authors:  Christopher J Martyniuk; Bin Fang; John M Koomen; Terrence Gavin; Lihai Zhang; David S Barber; Richard M Lopachin
Journal:  Chem Res Toxicol       Date:  2011-11-29       Impact factor: 3.739

9.  Neurotoxicity of acrylamide and related compounds in rats. Effects on rotarod performance, morphology of nerves and neurotubulin.

Authors:  H Tanii; K Hashimoto
Journal:  Arch Toxicol       Date:  1983-11       Impact factor: 5.153

10.  In vitro binding of [14C]2,5-hexanedione to rat neuronal cytoskeletal proteins.

Authors:  C L Lanning; K R Wilmarth; M B Abou-Donia
Journal:  Neurochem Res       Date:  1994-09       Impact factor: 3.996

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