Literature DB >> 7155786

Determination of amygdalin and its major metabolite prunasin in plasma and urine by high pressure liquid chromatography.

A G Rauws, L G Gramberg, M Olling.   

Abstract

A method is described for the determination of amygdalin and prunasin in plasma ultrafiltrate and urine. Both compounds are separated by high pressure liquid chromatography on a reversed phase column and subsequently detected at 215 nm. The identity of an amygdalin metabolite with prunasin was confirmed by mass spectrometry.

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Year:  1982        PMID： 7155786     DOI： 10.1007/bf01959135

Source DB:  PubMed          Journal:  Pharm Weekbl Sci        ISSN： 0167-6555


  7 in total

1.  Laetrile toxicity studies in dogs.

Authors:  E S Schmidt; G W Newton; S M Sanders; J P Lewis; E E Conn
Journal:  JAMA       Date:  1978-03-06       Impact factor: 56.272

2.  Role of the gastrointestinal microflora in amygdalin (laetrile)-induced cyanide toxicity.

Authors:  J H Carter; M A McLafferty; P Goldman
Journal:  Biochem Pharmacol       Date:  1980-02       Impact factor: 5.858

3.  Pharmacology of amygdalin (laetrile) in cancer patients.

Authors:  M M Ames; T P Moyer; J S Kovach; C G Moertel; J Rubin
Journal:  Cancer Chemother Pharmacol       Date:  1981       Impact factor: 3.333

4.  The pharmacokinetics of amygdalin.

Authors:  A G Rauws; M Olling; A Timmerman
Journal:  Arch Toxicol       Date:  1982-03       Impact factor: 5.153

5.  Studies of amygdalin (laetrile) toxicity in rodents.

Authors:  J D Khandekar; H Edelman
Journal:  JAMA       Date:  1979-07-13       Impact factor: 56.272

6.  A pharmacologic and toxicological study of amygdalin.

Authors:  C G Moertel; M M Ames; J S Kovach; T P Moyer; J R Rubin; J H Tinker
Journal:  JAMA       Date:  1981-02-13       Impact factor: 56.272

7.  A simple method for the estimation of amygdalin in the urine.

Authors:  K P Flora; J C Cradock; M M Ames
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1978-05
  7 in total

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