Literature DB >> 7150235

Removal of iron from diferric rabbit serum transferrin by rabbit reticulocytes.

S Heaphy, J Williams.   

Abstract

When radioiron-labelled transferrin with 55Fe located predominantly in the N-terminal iron-binding site and 59Fe predominantly in the C-terminal iron-binding site was incubated with rabbit reticulocytes, both radioisotopes of iron were removed at similar rates. Electrophoresis of transferrin samples taken during the course of an incubation, in polyacrylamide gels containing 6 M-urea, showed that iron was removed in a pairwise fashion, giving rise to iron-free transferrin.

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Year:  1982        PMID: 7150235      PMCID: PMC1158529          DOI: 10.1042/bj2050619

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  13 in total

1.  Functional equivalence of the two iron-binding sites of human transferrin.

Authors:  D C Harris; P Aisen
Journal:  Nature       Date:  1975-10-30       Impact factor: 49.962

2.  Function of transferrin.

Authors:  J Fletcher; E R Huehns
Journal:  Nature       Date:  1968-06-29       Impact factor: 49.962

3.  Interaction of human diferric transferrin with reticulocytes.

Authors:  H Huebers; E Csiba; B Josephson; E Huebers; C Finch
Journal:  Proc Natl Acad Sci U S A       Date:  1981-01       Impact factor: 11.205

4.  In vivo evidence for the functional heterogeneity of transferrin-bound iron. V. Isotransferrins: an explanation of the Fletcher-Huehns phenomenon in the rat.

Authors:  S Okada; B Jarvis; E B Brown
Journal:  J Lab Clin Med       Date:  1979-02

5.  No functional difference of the two iron-binding sites of human transferrin in vitro.

Authors:  C Van der Heul; M J Kroos; W L Van Noort; H G Van Eijk
Journal:  Clin Sci (Lond)       Date:  1981-02       Impact factor: 6.124

6.  Significance of the binding of iron by transferrin.

Authors:  J Fletcher; E R Huehns
Journal:  Nature       Date:  1967-08-05       Impact factor: 49.962

7.  Functional equivalence of iron bound to human transferrin at low pH or high pH.

Authors:  D C Harris
Journal:  Biochim Biophys Acta       Date:  1977-02-28

8.  Iron-donating properties of transferrin.

Authors:  D C Harris; P Aisen
Journal:  Biochemistry       Date:  1975-01-28       Impact factor: 3.162

9.  The behavior of transferrin iron in the rat.

Authors:  H Huebers; W Bauer; E Huebers; E Csiba; C Finch
Journal:  Blood       Date:  1981-02       Impact factor: 22.113

10.  Evidence for the functional heterogeneity of the two sites of transferrin in vitro.

Authors:  J van Baarlen; J T Brouwer; A Leibman; P Aisen
Journal:  Br J Haematol       Date:  1980-11       Impact factor: 6.998

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  1 in total

1.  Occupancy of the iron binding sites of human transferrin.

Authors:  H A Huebers; B Josephson; E Huebers; E Csiba; C A Finch
Journal:  Proc Natl Acad Sci U S A       Date:  1984-07       Impact factor: 11.205

  1 in total

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