Literature DB >> 7140721

Coproporphyrinogen III oxidase assay.

B Grandchamp, Y Nordmann.   

Abstract

An assay for coproporphyrinogen oxidase activity is described which uses a [14C]-coproporphyrinogen substrate with product isolation by methylation, extraction, and thin layer chromatography. This method affords high sensitivity, since a high specific activity of the substrate and good reproducibility due to the incorporation of an internal standard can be obtained. The activity in rat liver and human lymphocytes was found to be 140 nmol protoporphyrin/h/g of liver and 483 pmol protoporphyrin/h/mg of lymphocyte protein, respectively.

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Year:  1982        PMID： 7140721     DOI： 10.1159/000459102

Source DB:  PubMed          Journal:  Enzyme        ISSN： 0013-9432


  8 in total

1.  Coexistent hereditary coproporphyria and congenital erythropoietic porphyria (Günther disease).

Authors:  Y Nordmann; D Amram; J C Deybach; L N Phung; D Lesbros
Journal:  J Inherit Metab Dis       Date:  1990       Impact factor: 4.982

2.  A novel point mutation in congenital erythropoietic porphyria in two members of Japanese family.

Authors:  K Tanigawa; M Bensidhoum; N Takamura; H Namba; S Yamashita; H de Verneuil; C Ged
Journal:  Hum Genet       Date:  1996-05       Impact factor: 4.132

3.  A high-performance-liquid-chromatographic method for the assay of coproporphyrinogen oxidase activity in rat liver.

Authors:  F Li; C K Lim; T J Peters
Journal:  Biochem J       Date:  1986-10-15       Impact factor: 3.857

4.  Harderoporphyria: a variant hereditary coproporphyria.

Authors:  Y Nordmann; B Grandchamp; H de Verneuil; L Phung; B Cartigny; G Fontaine
Journal:  J Clin Invest       Date:  1983-09       Impact factor: 14.808

5.  Assignment of the human coproporphyrinogen oxidase to chromosome 9.

Authors:  B Grandchamp; D Weil; Y Nordmann; N Van Cong; H de Verneuil; C Foubert; M S Gross
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

Review 6.  Environmental chemical exposures and disturbances of heme synthesis.

Authors:  W E Daniell; H L Stockbridge; R F Labbe; J S Woods; K E Anderson; D M Bissell; J R Bloomer; R D Ellefson; M R Moore; C A Pierach; W E Schreiber; A Tefferi; G M Franklin
Journal:  Environ Health Perspect       Date:  1997-02       Impact factor: 9.031

7.  Direct assay of enzymes in heme biosynthesis for the detection of porphyrias by tandem mass spectrometry. Uroporphyrinogen decarboxylase and coproporphyrinogen III oxidase.

Authors:  Yuesong Wang; Paula Gatti; Martin Sadílek; C Ronald Scott; Frantisek Turecek; Michael H Gelb
Journal:  Anal Chem       Date:  2008-02-23       Impact factor: 6.986

8.  Coordinate expression of coproporphyrinogen oxidase and cytochrome c6 in the green alga Chlamydomonas reinhardtii in response to changes in copper availability.

Authors:  K L Hill; S Merchant
Journal:  EMBO J       Date:  1995-03-01       Impact factor: 11.598
  8 in total

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