Literature DB >> 7126267

Prediction of intestinal first-pass effect of phenacetin in the rat from enzyme kinetic data--correlation with in vivo data using mucosal blood flow.

P Klippert, P Borm, J Noordhoek.   

Abstract

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 7126267     DOI： 10.1016/0006-2952(82)90068-5

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN： 0006-2952            Impact factor:   5.858


× No keyword cloud information.
  5 in total

Review 1.  The mucosa of the small intestine: how clinically relevant as an organ of drug metabolism?

Authors:  Margaret M Doherty; William N Charman
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

2.  Enzymatic activities in the microsomes prepared from rat small intestinal epithelial cells by differential procedures.

Authors:  K Mohri; Y Uesawa
Journal:  Pharm Res       Date:  2001-08       Impact factor: 4.200

3.  Comparison of CYP2D6 content and metoprolol oxidation between microsomes isolated from human livers and small intestines.

Authors:  S Madani; M F Paine; L Lewis; K E Thummel; D D Shen
Journal:  Pharm Res       Date:  1999-08       Impact factor: 4.200

4.  A physiologically based pharmacokinetic analysis of capecitabine, a triple prodrug of 5-FU, in humans: the mechanism for tumor-selective accumulation of 5-FU.

Authors:  Y Tsukamoto; Y Kato; M Ura; I Horii; H Ishitsuka; H Kusuhara; Y Sugiyama
Journal:  Pharm Res       Date:  2001-08       Impact factor: 4.200

Review 5.  Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical Models.

Authors:  Sheila Annie Peters; Christopher R Jones; Anna-Lena Ungell; Oliver J D Hatley
Journal:  Clin Pharmacokinet       Date:  2016-06       Impact factor: 6.447
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.