Literature DB >> 11587497

Enzymatic activities in the microsomes prepared from rat small intestinal epithelial cells by differential procedures.

K Mohri1, Y Uesawa.   

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Year:  2001        PMID： 11587497     DOI： 10.1023/a:1010951732288

Source DB:  PubMed          Journal:  Pharm Res        ISSN： 0724-8741            Impact factor:   4.200


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  17 in total

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2.  In vivo disposition and metabolism by liver and enterocyte microsomes of the antitubercular drug rifabutin in rats.

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3.  Prediction of intestinal first-pass effect of phenacetin in the rat from enzyme kinetic data--correlation with in vivo data using mucosal blood flow.

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4.  Tacrolimus oral bioavailability doubles with coadministration of ketoconazole.

Authors:  L C Floren; I Bekersky; L Z Benet; Q Mekki; D Dressler; J W Lee; J P Roberts; M F Hebert
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5.  Cyclosporine metabolism by P450IIIA in rat enterocytes--another determinant of oral bioavailability?

Authors:  J C Kolars; P L Stetson; B D Rush; M J Ruwart; P Schmiedlin-Ren; E A Duell; J J Voorhees; P B Watkins
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6.  Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism.

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7.  Differential induction of prehepatic and hepatic metabolism of verapamil by rifampin.

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Journal:  Hepatology       Date:  1996-10       Impact factor: 17.425

8.  Steroid metabolism by rabbit olfactory-specific P450 2G1.

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9.  Rat small intestinal cytochromes P450 probed by warfarin metabolism.

Authors:  M J Fasco; J B Silkworth; D A Dunbar; L S Kaminsky
Journal:  Mol Pharmacol       Date:  1993-02       Impact factor: 4.436

10.  The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine.

Authors:  D Y Gomez; V J Wacher; S J Tomlanovich; M F Hebert; L Z Benet
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2.  Modulation of CYP3a expression and activity in mice models of type 1 and type 2 diabetes.

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4.  Optimization of intestinal microsomal preparation in the rat: A systematic approach to assess the influence of various methodologies on metabolic activity and scaling factors.

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5.  Quantifying gut wall metabolism: methodology matters.

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6.  Characterization of Porcine Hepatic and Intestinal Drug Metabolizing CYP450: Comparison with Human Orthologues from A Quantitative, Activity and Selectivity Perspective.

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7.  Overexpression of P-glycoprotein, MRP2, and CYP3A4 impairs intestinal absorption of octreotide in rats with portal hypertension.

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  7 in total

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