| Literature DB >> 7125593 |
Abstract
Genetic polymorphism of coagulation factor XIIIB subunit in Japanese has been described, using a thin-layer agarose gel isoelectric focusing followed by immunofixation. Phenotypes of factor XIIIB subunit were essentially classified into three common patterns A, B and AB. It is estimated that the phenotypes are determined by two codominant alleles. A new rare variant B' has been detected in Japanese. Gene frequencies calculated from 304 individuals showed FXIII-BA = 0.735, FXIII-BB = 0.252 and FXIII-BB' = 0.013, respectively. The distribution of phenotypes fitted the Hardy-Weinberg equilibrium.Entities:
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Year: 1982 PMID： 7125593 DOI： 10.1111/j.1469-1809.1982.tb00712.x
Source DB: PubMed Journal: Ann Hum Genet ISSN： 0003-4800 Impact factor: 1.670