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Literature DB >> 3467588

Genetic studies of low abundance human plasma proteins. II. Population genetics of coagulation factor XIIIB.

Abstract

Plasma samples from a large number of different ethnic groups, consisting of U.S. whites, U.S. blacks, Eskimos from Kodiak and St. Lawrence Island, Aleuts of the Pribilof Islands, and three Amerindian groups from Canada and Mexico have been analyzed by isoelectric focusing followed by immunoblotting to determine the magnitude of genetic variation at the F XIIIB structural locus. The synthesis of published data and our new data demonstrate remarkable variation in the distribution of the three common alleles at this locus and establishes F XIIIB as an extremely informative marker for population differentiation and evolutionary studies. Genetic distance analysis based on this variation separates Caucasian, black, and Mongoloid populations into three distinct clusters.

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Year: 1986 PMID： 3467588 PMCID： PMC1684128

Source DB: PubMed Journal: Am J Hum Genet ISSN： 0002-9297 Impact factor: 11.025

15 in total

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Authors: P Kreckel; P Kühnl
Journal: Blut Date: 1982-11

8 in total

1. Polymorphism of coagulation factor XIII B subunit: further occurrence of FXIIIB*15 in Japanese and phenotyping in bloodstains.

Authors: N Komatsu; A Kido; Y Kimura; M Oya; Y Dobashi; K Hashimoto
Journal: Int J Legal Med Date: 1992 Impact factor: 2.686

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Journal: Z Rechtsmed Date: 1989

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Journal: Am J Hum Genet Date: 1989-01 Impact factor: 11.025

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Authors: Anthony W Ryan; David A Hughes; Kun Tang; Dermot P Kelleher; Thomas Ryan; Ross McManus; Mark Stoneking
Journal: Eur J Hum Genet Date: 2008-08-20 Impact factor: 4.246

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Journal: Am J Hum Genet Date: 1991-12 Impact factor: 11.025

8 in total