| Literature DB >> 7122908 |
H Bisgaard, J Kristensen, J Søndergaard.
Abstract
Using a laser-Doppler-flowmeter the microvascular response to LTC4 and LTD4 was measured. Intradermal injection of 1 microgram LTC4 and LTD4 caused an increase in the microvascular cutaneous bloodflow. The increase in flow was equal to that caused by histamine in equimolar amounts. Blocking the triple-response did not change the response. The values measured after injection of histamine and leucotrienes were about 10-15 times the values found in undisturbed skin and represents probably a maximally dilated vascular bed. Injection of the leucotrienes caused a slight sensation of pain.Entities:
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Year: 1982 PMID： 7122908 DOI： 10.1016/0090-6980(82)90124-1
Source DB: PubMed Journal: Prostaglandins ISSN： 0090-6980