Literature DB >> 7115330

Sensitivity of brown-adipose-tissue carnitine palmitoyltransferase to inhibition by malonyl-CoA.

E D Saggerson, C A Carpenter.   

Abstract

Overt carnitine palmitoyltransferase in mitochondria isolated from interscapular brown adipose tissue of cold-adapted rats or rats maintained at normal temperature is extremely sensitive to inhibition by malonyl-CoA.

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Year:  1982        PMID： 7115330      PMCID： PMC1158357          DOI： 10.1042/bj2040373

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  10 in total

1.  Development of mitochondrial energy metabolism in rat brain.

Authors:  J M Land; R F Booth; R Berger; J B Clark
Journal:  Biochem J       Date:  1977-05-15       Impact factor: 3.857

2.  Evidence that fatty acid synthesis in the interscapular brown adipose tissue of cold-adapted rats is increased in vivo by insulin by mechanisms involving parallel activation of pyruvate dehydrogenase and acetyl-coenzyme A carboxylase.

Authors:  J G McCormack; R M Denton
Journal:  Biochem J       Date:  1977-09-15       Impact factor: 3.857

Review 3.  Brown adipose tissue mitochondria.

Authors:  D G Nicholls
Journal:  Biochim Biophys Acta       Date:  1979-07-03

Review 4.  Regulation of hepatic fatty acid oxidation and ketone body production.

Authors:  J D McGarry; D W Foster
Journal:  Annu Rev Biochem       Date:  1980       Impact factor: 23.643

5.  Malonyl CoA inhibition of carnitine acyltransferase activities: effects of thiol-group reagents.

Authors:  E D Saggerson; C A Carpenter
Journal:  FEBS Lett       Date:  1982-01-11       Impact factor: 4.124

6.  Carnitine acyltransferase activities in rat liver and heart measured with palmitoyl-CoA and octanoyl-CoA. Latency, effects of K+, bivalent metal ions and malonyl-CoA.

Authors:  E D Saggerson
Journal:  Biochem J       Date:  1982-02-15       Impact factor: 3.857

7.  Fatty acid synthesis in vivo in brown adipose tissue, liver and white adipose tissue of the cold-acclimated rat.

Authors:  P Trayhurn
Journal:  FEBS Lett       Date:  1979-08-01       Impact factor: 4.124

8.  Carnitine palmitoyltransferase I. The site of inhibition of hepatic fatty acid oxidation by malonyl-CoA.

Authors:  J D McGarry; G F Leatherman; D W Foster
Journal:  J Biol Chem       Date:  1978-06-25       Impact factor: 5.157

9.  Some aspects of fatty acid oxidation in isolated fat-cell mitochondria from rat.

Authors:  R D Harper; E D Saggerson
Journal:  Biochem J       Date:  1975-12       Impact factor: 3.857

10.  Lipogenesis in interscapular brown adipose tissue of virgin, pregnant and lactating rats. The effects of intragastric feeding.

Authors:  L Agius; D H Williamson
Journal:  Biochem J       Date:  1980-08-15       Impact factor: 3.857
  10 in total
  13 in total

1.  Intertissue differences in the hysteretic behaviour of carnitine palmitoyltransferase in the presence of malonyl-CoA.

Authors:  A C Lloyd; C A Carpenter; E D Saggerson
Journal:  Biochem J       Date:  1986-07-01       Impact factor: 3.857

2.  Activities of enzymes of glycerolipid synthesis in brown adipose tissue after treatment of rats with the adrenergic agonists BRL 26830A and phenylephrine, after exposure to cold and in streptozotocin-diabetes.

Authors:  J R Mitchell; E D Saggerson
Journal:  Biochem J       Date:  1991-08-01       Impact factor: 3.857

3.  The effect of malonyl-CoA on overt and latent carnitine acyltransferase activities in rat liver and adipocyte mitochondria.

Authors:  E D Saggerson; C A Carpenter
Journal:  Biochem J       Date:  1983-02-15       Impact factor: 3.857

4.  Comparison of triacylglycerol synthesis in rat brown and white adipocytes. Effects of hypothyroidism and streptozotocin-diabetes on enzyme activities and metabolic fluxes.

Authors:  H S Baht; E D Saggerson
Journal:  Biochem J       Date:  1988-03-01       Impact factor: 3.857

5.  Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis.

Authors:  Judith Simcox; Gisela Geoghegan; John Alan Maschek; Claire L Bensard; Marzia Pasquali; Ren Miao; Sanghoon Lee; Lei Jiang; Ian Huck; Erin E Kershaw; Anthony J Donato; Udayan Apte; Nicola Longo; Jared Rutter; Renate Schreiber; Rudolf Zechner; James Cox; Claudio J Villanueva
Journal:  Cell Metab       Date:  2017-09-05       Impact factor: 27.287

6.  Effects of DL-2-bromopalmitoyl-CoA and bromoacetyl-CoA in rat liver and heart mitochondria. Inhibition of carnitine palmitoyltransferase and displacement of [14C]malonyl-CoA from mitochondrial binding sites.

Authors:  M R Edwards; M I Bird; E D Saggerson
Journal:  Biochem J       Date:  1985-08-15       Impact factor: 3.857

7.  Carnitine palmitoyltransferase in liver and five extrahepatic tissues in the rat. Inhibition by DL-2-bromopalmitoyl-CoA and effect of hypothyroidism.

Authors:  E D Saggerson; C A Carpenter
Journal:  Biochem J       Date:  1986-05-15       Impact factor: 3.857

8.  Development and characterization of a polyclonal antibody against rat liver mitochondrial overt carnitine palmitoyltransferase (CPT I). Distinction of CPT I from CPT II and of isoforms of CPT I in different tissues.

Authors:  M P Kolodziej; P J Crilly; C G Corstorphine; V A Zammit
Journal:  Biochem J       Date:  1992-03-01       Impact factor: 3.857

9.  Effects of high-carbohydrate diets on lipogenesis in rat interscapular brown adipose tissue.

Authors:  P J Weaire; T F Kanagasabai
Journal:  Biochem J       Date:  1982-09-15       Impact factor: 3.857

10.  Regulation of fatty acid synthesis and malonyl-CoA content in mouse brown adipose tissue in response to cold-exposure, starvation or re-feeding.

Authors:  M G Buckley; E A Rath
Journal:  Biochem J       Date:  1987-04-15       Impact factor: 3.857
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