Literature DB >> 71152

Collagenase at sites of cartilage erosion in the rheumatoid joint.

D E Woolley, M J Crossley, J M Evanson.   

Abstract

Immunolocalization studies of rheumatoid tissues employing specific synovial collagenase antibody have demonstrated immunoreactive enzyme at the cartilage/pannus junction. Collagenase was not detected in chondrocytes or the cartilage matrix remote from the resorbing front, and relatively little enzyme was observed in the hypertrophied synovial membrane itself. These observations directly support the idea that synovial collagenase participates in cartilage erosion in rheumatoid arthritis.

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Year:  1977        PMID: 71152     DOI: 10.1002/art.1780200612

Source DB:  PubMed          Journal:  Arthritis Rheum        ISSN: 0004-3591


  55 in total

Review 1.  Synovial biopsy in arthritis research: five years of concerted European collaboration.

Authors:  B Bresnihan; P P Tak; P Emery; L Klareskog; F Breedveld
Journal:  Ann Rheum Dis       Date:  2000-07       Impact factor: 19.103

2.  Analysis of the cell infiltrate and expression of matrix metalloproteinases and granzyme B in paired synovial biopsy specimens from the cartilage-pannus junction in patients with RA.

Authors:  T J Smeets; M C Kraan; S Galjaard; P P Youssef; M D Smith; P P Tak
Journal:  Ann Rheum Dis       Date:  2001-06       Impact factor: 19.103

3.  Interaction of polymorphonuclear leucocytes with patellar cartilage of immobilised arthritic joints: a scanning electron microscopic study.

Authors:  P L van Lent; F H Wilms; W B van den Berg
Journal:  Ann Rheum Dis       Date:  1989-10       Impact factor: 19.103

4.  Degradation of cartilage proteoglycans by elastase is dependent on charge-mediated interactions.

Authors:  J Schalkwijk; L A Joosten; W B van den Berg; L B van de Putte
Journal:  Rheumatol Int       Date:  1988       Impact factor: 2.631

5.  Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice.

Authors:  U Müller-Ladner; J Kriegsmann; B N Franklin; S Matsumoto; T Geiler; R E Gay; S Gay
Journal:  Am J Pathol       Date:  1996-11       Impact factor: 4.307

6.  Pathology of collagen degradation. A review.

Authors:  R Pérez-Tamayo
Journal:  Am J Pathol       Date:  1978-08       Impact factor: 4.307

7.  Bidirectional erosion of cartilage in the rheumatoid knee joint.

Authors:  M Bromley; H Bertfield; J M Evanson; D E Woolley
Journal:  Ann Rheum Dis       Date:  1985-10       Impact factor: 19.103

8.  Rheumatoid inflammation and joint destruction: cause and effect or parallel phenomena?

Authors:  J D Williams; D L Scott; F B DeBrito; D A Willoughby; E C Huskisson
Journal:  Agents Actions       Date:  1986-08

9.  Polymorphonuclear granulocytes in rheumatic tissue destruction. III. an electron microscopic study of PMNs at the pannus-cartilage junction in rheumatoid arthritis.

Authors:  W Mohr; H Westerhellweg; D Wessinghage
Journal:  Ann Rheum Dis       Date:  1981-08       Impact factor: 19.103

10.  The inhibitory effects of antirheumatic drugs on the activity of human leukocyte elastase and cathepsin G.

Authors:  J Steinmeyer; D A Kalbhen
Journal:  Inflamm Res       Date:  1996-07       Impact factor: 4.575

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