Literature DB >> 7259331

Polymorphonuclear granulocytes in rheumatic tissue destruction. III. an electron microscopic study of PMNs at the pannus-cartilage junction in rheumatoid arthritis.

W Mohr, H Westerhellweg, D Wessinghage.   

Abstract

Metatarsophalangeal and metacarpophalangeal joints from 3 patients with rheumatoid arthritis were investigated electron microscopically with regard to the occurrence of polymorphonuclear granulocytes (PMNs) at the pannus-cartilage junction. In all 3 cases PMNs could be detected at the junction and within the cartilaginous matrix. PMN cytoplasmic processes surrounded collagenous islands in the cartilage. From the morphological findings it is deduced that PMNs are cells capable of destroying cartilage in inflammatory joint diseases, in particular in rheumatoid arthritis.

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Mesh：

Year:  1981        PMID： 7259331      PMCID： PMC1000735          DOI： 10.1136/ard.40.4.396

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN： 0003-4967            Impact factor:   19.103


  26 in total

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Journal:  Science       Date:  1978-05-19       Impact factor: 47.728

4.  Induction of the synthesis of latent collagenase and latent neutral protease in chondrocytes by a factor synthesized by activated macrophages.

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Journal:  Arthritis Rheum       Date:  1980-04

Review 5.  [Pathogenesis of inflammatory cartilage destruction in chronic polyarthritis].

Authors:  W Mohr
Journal:  Dtsch Med Wochenschr       Date:  1980-06-13       Impact factor: 0.628

6.  Heberden oration 1978. Recent studies on the control of joint damage: the contribution of the Strangeways Research Laboratory.

Authors:  J T Dingle
Journal:  Ann Rheum Dis       Date:  1979-06       Impact factor: 19.103

7.  Degradation of cartilage proteoglycan by human leukocyte granule neutral proteases--a model of joint injury. II. Degradation of isolated bovine nasal cartilage proteoglycan.

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Journal:  J Clin Invest       Date:  1976-03       Impact factor: 14.808

8.  [Neutrophil granulocytes in rheumatic tissue destruction].

Authors:  W Mohr; D Wessinghage; G Köhler
Journal:  Z Rheumatol       Date:  1980 Sep-Oct       Impact factor: 1.372

9.  [Pathogenesis of inflammatory cartilage destruction in adjuvant arthritis in the rat].

Authors:  W Mohr; A Wild; H P Wolf
Journal:  Z Rheumatol       Date:  1980 Jul-Aug       Impact factor: 1.372

10.  Metal-dependent neutral proteoglycanase activity from monolayer-cultured lapine articular chondrocytes.

Authors:  C J Malemud; G A Weitzman; D P Norby; A I Sapolsky; D S Howell
Journal:  J Lab Clin Med       Date:  1979-06
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  30 in total

1.  Enhanced capacity for release of leucotriene B4 by neutrophils in rheumatoid arthritis.

Authors:  J Elmgreen; O H Nielsen; I Ahnfelt-Rønne
Journal:  Ann Rheum Dis       Date:  1987-07       Impact factor: 19.103

2.  Subnormal sensitivity of neutrophils to complement split product C5a in rheumatoid arthritis: relation to complement catabolism and disease extent.

Authors:  J Elmgreen; T M Hansen
Journal:  Ann Rheum Dis       Date:  1985-08       Impact factor: 19.103

3.  Human synovial lubricin expresses sialyl Lewis x determinant and has L-selectin ligand activity.

Authors:  Chunsheng Jin; Anna-Karin Hultgård Ekwall; Johan Bylund; Lena Björkman; Ruby P Estrella; John M Whitelock; Thomas Eisler; Maria Bokarewa; Niclas G Karlsson
Journal:  J Biol Chem       Date:  2012-08-28       Impact factor: 5.157

4.  Improvement in rheumatoid arthritis following application of an extracorporeal granulotrap column, G-1.

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Journal:  Rheumatol Int       Date:  1996       Impact factor: 2.631

5.  IRF5 controls both acute and chronic inflammation.

Authors:  Miriam Weiss; Adam J Byrne; Katrina Blazek; David G Saliba; James E Pease; Dany Perocheau; Marc Feldmann; Irina A Udalova
Journal:  Proc Natl Acad Sci U S A       Date:  2015-08-17       Impact factor: 11.205

6.  Plasma and synovial fluid levels of granulocytal elastase-alpha-1-protease inhibitor complex in patients with rheumatoid arthritis.

Authors:  K Kuramitsu; A Yoshida
Journal:  Rheumatol Int       Date:  1990       Impact factor: 2.631

7.  Functions of polymorphonuclear leukocytes in early rheumatoid arthritis.

Authors:  M Leirisalo-Repo; L Paimela; S Koskimies; H Repo
Journal:  Inflammation       Date:  1993-08       Impact factor: 4.092

8.  Effect of taurine chloramine on the production of matrix metalloproteinases (MMPs) in adiponectin- or IL-1beta-stimulated fibroblast-like synoviocytes.

Authors:  Kyoung Soo Kim; Hyun-Mi Choi; Da Hee Oh; Chaekyun Kim; Jin Seok Jeong; Myung Chul Yoo; Hyung-In Yang
Journal:  J Biomed Sci       Date:  2010-08-24       Impact factor: 8.410

9.  Conditioned medium from stimulated mononuclear leucocytes potentiates the ability of human neutrophils to damage human articular cartilage.

Authors:  E J Bates; I C Kowanko; A Ferrante
Journal:  Ann Rheum Dis       Date:  1988-01       Impact factor: 19.103

10.  Distribution of lysozyme in synovial tissue of patients with osteoarthritis and rheumatoid arthritis demonstrated by different enzyme histochemical methods.

Authors:  P Fritz; J Müller; U Braun; W Laschner; J G Saal; H Rautenstrauch; H Reiser
Journal:  Rheumatol Int       Date:  1982       Impact factor: 2.631
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