Literature DB >> 7107521

Chemical modification of everninomicins.

A K Ganguly, V M Girijavallabhan, G H Miller, O Z Sarre.   

Abstract

Novel antibiotic everninomicin D is chemically transformed into new biologically active derivatives. Reactions of a nitro group attached to a tertiary carbon center have been investigated. Synthesis and reactions of hydroxylaminoeverninomicin D, aminoeverninomicin D and their derivatives have been discussed.

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Year:  1982        PMID: 7107521     DOI: 10.7164/antibiotics.35.561

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  11 in total

1.  Multiple-stage mass spectrometric analysis of complex oligosaccharide antibiotics (everninomicins) in a quadrupole ion trap.

Authors:  Guodong Chen; Birendra N Pramanik; Peter L Bartner; Anil K Saksena; Michael L Gross
Journal:  J Am Soc Mass Spectrom       Date:  2002-11       Impact factor: 3.109

Review 2.  The structural biology of enzymes involved in natural product glycosylation.

Authors:  Shanteri Singh; George N Phillips; Jon S Thorson
Journal:  Nat Prod Rep       Date:  2012-06-12       Impact factor: 13.423

3.  Structure and mechanism of ORF36, an amino sugar oxidizing enzyme in everninomicin biosynthesis .

Authors:  Jessica L Vey; Ahmad Al-Mestarihi; Yunfeng Hu; Michael A Funk; Brian O Bachmann; T M Iverson
Journal:  Biochemistry       Date:  2010-11-02       Impact factor: 3.162

4.  Evernimicin binds exclusively to the 50S ribosomal subunit and inhibits translation in cell-free systems derived from both gram-positive and gram-negative bacteria.

Authors:  P M McNicholas; D J Najarian; P A Mann; D Hesk; R S Hare; K J Shaw; T A Black
Journal:  Antimicrob Agents Chemother       Date:  2000-05       Impact factor: 5.191

5.  Mutations in ribosomal protein L16 conferring reduced susceptibility to evernimicin (SCH27899): implications for mechanism of action.

Authors:  P V Adrian; W Zhao; T A Black; K J Shaw; R S Hare; K P Klugman
Journal:  Antimicrob Agents Chemother       Date:  2000-03       Impact factor: 5.191

6.  Nucleotide sequence of a complete ribosomal spacer of D. melanogaster.

Authors:  A Simeone; A La Volpe; E Boncinelli
Journal:  Nucleic Acids Res       Date:  1985-02-25       Impact factor: 16.971

7.  Evernimicin (SCH27899) inhibits both translation and 50S ribosomal subunit formation in Staphylococcus aureus cells.

Authors:  W S Champney; C L Tober
Journal:  Antimicrob Agents Chemother       Date:  2000-06       Impact factor: 5.191

8.  Evernimicin (SCH27899) inhibits a novel ribosome target site: analysis of 23S ribosomal DNA mutants.

Authors:  P V Adrian; C Mendrick; D Loebenberg; P McNicholas; K J Shaw; K P Klugman; R S Hare; T A Black
Journal:  Antimicrob Agents Chemother       Date:  2000-11       Impact factor: 5.191

Review 9.  Increasing carbohydrate diversity via amine oxidation: aminosugar, hydroxyaminosugar, nitrososugar, and nitrosugar biosynthesis in bacteria.

Authors:  Shannon C Timmons; Jon S Thorson
Journal:  Curr Opin Chem Biol       Date:  2008-04-18       Impact factor: 8.822

10.  Intervening sequences in the ribosomal RNA genes of Ascaris lumbricoides: DNA sequences at junctions and genomic organization.

Authors:  E Back; E Van Meir; F Müller; D Schaller; H Neuhaus; P Aeby; H Tobler
Journal:  EMBO J       Date:  1984-11       Impact factor: 11.598

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