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Literature DB >> 7104162

A comparative study of saliva and serum paracetamol levels using a simple spectrophotometric method.

Abstract

The relationship between saliva and serum paracetamol levels was investigated in ten healthy male volunteers. The salivary and serum paracetamol levels showed significant correlation with each other. The salivary and serum paracetamol concentration ratio was highly dependent on sampling time. The salivary and serum paracetamol half-lives showed significant correlation with each other while the area under curve of paracetamol concentration in saliva and serum failed to show significant correlation.

Entities: Chemical

Mesh：

Substances：
Acetaminophen

Year: 1982 PMID： 7104162 PMCID： PMC1427583 DOI： 10.1111/j.1365-2125.1982.tb04944.x

Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335

3 in total

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Authors: M Danhof; D D Breimer
Journal: Clin Pharmacokinet Date: 1978 Jan-Feb Impact factor: 6.447

2. A rapid, simple acetaminophen spectrophotometric determination.

Authors: J N Miceli; M K Aravind; A K Done
Journal: Pediatrics Date: 1979-04 Impact factor: 7.124

3. Salivary excretion of paracetamol in man.

Authors: J P Glynn; W Bastain
Journal: J Pharm Pharmacol Date: 1973-05 Impact factor: 3.765

3 in total

15 in total

1. A comparison of serum and saliva paracetamol concentrations.

Authors: M Smith; E Whitehead; G O'Sullivan; F Reynolds
Journal: Br J Clin Pharmacol Date: 1991-05 Impact factor: 4.335

2. Is one paracetamol suppository of 1000 mg bioequivalent with two suppositories of 500 mg.

Authors: T Närvänen; M Halsas; J Smal; M Marvola
Journal: Eur J Drug Metab Pharmacokinet Date: 1998 Apr-Jun Impact factor: 2.441

3. Salivary paracetamol elimination kinetics during the menstrual cycle.

Authors: L Somaja; J Thangam
Journal: Br J Clin Pharmacol Date: 1987-03 Impact factor: 4.335

4. UGT1A6 and UGT2B15 polymorphisms and acetaminophen conjugation in response to a randomized, controlled diet of select fruits and vegetables.

Authors: Sandi L Navarro; Yu Chen; Lin Li; Shuying S Li; Jyh-Lurn Chang; Yvonne Schwarz; Irena B King; John D Potter; Jeannette Bigler; Johanna W Lampe
Journal: Drug Metab Dispos Date: 2011-06-10 Impact factor: 3.922

5. A double-blind placebo controlled study to examine effects of sucralfate on paracetamol absorption.

Authors: F Kamali; J R Fry; H L Smart; G D Bell
Journal: Br J Clin Pharmacol Date: 1985-01 Impact factor: 4.335

6. Influence of renal insufficiency on the pharmacokinetics of cicletanine and its effects on the urinary excretion of electrolytes and prostanoids.

Authors: N Ferry; J Geoffroy; N Pozet; G Cuisinaud; D Benzoni; P Y Zech; J Sassard
Journal: Br J Clin Pharmacol Date: 1988-03 Impact factor: 4.335

7. Correlation of paired toxic plasma and saliva paracetamol concentrations following deliberate self-poisoning with paracetamol.

Authors: Jessamine H Soderstrom; Daniel M Fatovich; Christine Mandelt; Sam Vasikaran; David L McCoubrie; Frank F Daly; Sally A Burrows
Journal: Br J Clin Pharmacol Date: 2012-07 Impact factor: 4.335