Literature DB >> 7103489

Mutagenicity of anthraquinone and hydroxylated anthraquinones in the Ames/Salmonella microsome system.

D F Liberman, R C Fink, F L Schaefer, R J Mulcahy, A A Stark.   

Abstract

The mutagenicity of anthracene, anthraquinone, and four structurally similar compounds of each was evaluated in the Ames/Salmonella microsome assay. Anthraquinone was shown to be mutagenic for strains TA1537, TA1538, and TA98 in the absence of rat liver homogenate. The four anthraquinone derivatives tested were mutagenic for TA1537 exclusively. None of the anthracenes exhibited mutagenic activity.

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Year:  1982        PMID： 7103489      PMCID： PMC244239          DOI： 10.1128/aem.43.6.1354-1359.1982

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  7 in total

1.  Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test.

Authors:  B N Ames; J Mccann; E Yamasaki
Journal:  Mutat Res       Date:  1975-12       Impact factor: 2.433

2.  Mutagenicity of the mycotoxin emodin in the salmonella/microsome system.

Authors:  F C Wehner; P G Thiel; M du Rand
Journal:  Appl Environ Microbiol       Date:  1979-03       Impact factor: 4.792

3.  Mutagenicity of anthraquinone and benzanthrone derivatives in the Salmonella/microsome test: activation of anthraquinone glycosides by enzymic extracts of rat cecal bacteria.

Authors:  J P Brown; P S Dietrich
Journal:  Mutat Res       Date:  1979-01       Impact factor: 2.433

4.  Mutagenesis by 9,10-anthraquinone derivatives and related compounds in Salmonella typhimurium.

Authors:  J P Brown; R J Brown
Journal:  Mutat Res       Date:  1976-07       Impact factor: 2.433

5.  Mutagenicity of anthraquinone and azo dyes in Ames' Salmonella typhimurium test.

Authors:  S Venturini; M Tamaro
Journal:  Mutat Res       Date:  1979-12       Impact factor: 2.433

6.  Mutagenicity of islandicin and chrysophanol in the Salmonella/microsome system.

Authors:  D F Liberman; F L Schaefer; R C Fink; M Ramgopal; A C Ghosh; R Mulcahy
Journal:  Appl Environ Microbiol       Date:  1980-09       Impact factor: 4.792

Review 7.  A review of the genetic effects of naturally occurring flavonoids, anthraquinones and related compounds.

Authors:  J P Brown
Journal:  Mutat Res       Date:  1980-05       Impact factor: 2.433
  7 in total
  3 in total

1.  Genotoxicity in the hepatocyte/DNA repair test and toxicity to liver mitochondria of 1-hydroxyanthraquinone and several dihydroxyanthraquinones.

Authors:  K Kawai; H Mori; S Sugie; N Yoshimi; T Inoue; T Nakamaru; Y Nozawa; T Matsushima
Journal:  Cell Biol Toxicol       Date:  1986-12       Impact factor: 6.691

2.  Mutagenicity of quinones: pathways of metabolic activation and detoxification.

Authors:  P L Chesis; D E Levin; M T Smith; L Ernster; B N Ames
Journal:  Proc Natl Acad Sci U S A       Date:  1984-03       Impact factor: 11.205

Review 3.  Biophysical Characterization and Anticancer Activities of Photosensitive Phytoanthraquinones Represented by Hypericin and Its Model Compounds.

Authors:  Valéria Verebová; Jiří Beneš; Jana Staničová
Journal:  Molecules       Date:  2020-12-01       Impact factor: 4.411
  3 in total

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