Literature DB >> 709177

Drug treatment of psychiatric patients in general practice.

P Tyrer.   

Abstract

The prescribing of psychotropic drugs by general practitioners was assessed by analysing the drug treatment of all patients referred from general practice to a psychiatric outpatient clinic over four years. Of the 287 patients, 220 were taking one or more of 56 different psychotropic drugs at referral, diazepam being the most common. Benzodiazepines and barbiturates had been taken for significantly longer than other drugs, and, of a total of 342 drugs, 61 had been prescribed regularly for over a year. Half of the drugs were considered to be incorrectly prescribed on pharmacological grounds, the main errors being unnecessarily prolonged regular treatment, incorrect dosage (particularly common with antidepressants), and polypharmacy with drugs of similar pharmacological action. A basic grounding in the pharmacology of psychotropic drugs might help practitioners to avoid prescribing errors of this kind.

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Year:  1978        PMID: 709177      PMCID: PMC1607938          DOI: 10.1136/bmj.2.6143.1008

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  11 in total

1.  Pills for personal problems.

Authors:  W H Trethowan
Journal:  Br Med J       Date:  1975-09-27

2.  Effects of maintenance amitriptyline and psychotherapy on symptoms of depression.

Authors:  E S Paykel; A Dimascio; D Haskell; B A Prusoff
Journal:  Psychol Med       Date:  1975-02       Impact factor: 7.723

3.  Use of medicines in general practice.

Authors:  D C Skegg; R Doll; J Perry
Journal:  Br Med J       Date:  1977-06-18

4.  An evaluation of continuation therapy with tricyclic antidepressants in depressive illness.

Authors:  R H Mindham; C Howland; M Shepherd
Journal:  Psychol Med       Date:  1973-02       Impact factor: 7.723

5.  Prazepam, a precursor of desmethyldiazepam.

Authors:  D J Greenblatt; R I Shader
Journal:  Lancet       Date:  1978-04-01       Impact factor: 79.321

6.  The benzodiazepine bonanza.

Authors:  P Tyrer
Journal:  Lancet       Date:  1974-09-21       Impact factor: 79.321

7.  The physician's knowledge of psychotropic drugs: preliminary results.

Authors:  R M Gottlieb; T Nappi; J J Strain
Journal:  Am J Psychiatry       Date:  1978-01       Impact factor: 18.112

8.  Benzodiazepines and withdrawal psychosis. Report of three cases.

Authors:  S H Preskorn; L J Denner
Journal:  JAMA       Date:  1977-01-03       Impact factor: 56.272

9.  Mianserin in the treatment of depressive illness and anxiety states in general practice.

Authors:  J E Murphy
Journal:  Br J Clin Pharmacol       Date:  1978       Impact factor: 4.335

10.  Polypharmacy among psychiatric patients.

Authors:  E Hemminki
Journal:  Acta Psychiatr Scand       Date:  1977-11       Impact factor: 6.392

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  18 in total

Review 1.  Is there still a role for benzodiazepines in general practice?

Authors:  M B King
Journal:  Br J Gen Pract       Date:  1992-05       Impact factor: 5.386

2.  Unrecognized depression in general practice.

Authors:  R H Burton; P Freeling
Journal:  J R Coll Gen Pract Occas Pap       Date:  1987-09

3.  Double-blind placebo-controlled trial of amitriptyline among depressed patients in general practice.

Authors:  J A Hollyman; P Freeling; E S Paykel; A Bhat; P Sedgwick
Journal:  J R Coll Gen Pract       Date:  1988-09

4.  Benzodiazepine prescriptions and therapist non-compliance.

Authors:  B Geiselmann; M Linden; N Sachs-Ericsson
Journal:  Eur Arch Psychiatry Neurol Sci       Date:  1989

Review 5.  Constraints on antidepressant prescribing and principles of cost-effective antidepressant use. Part 1: Depression and its treatment.

Authors:  J A Henry; C A Rivas
Journal:  Pharmacoeconomics       Date:  1997-05       Impact factor: 4.981

6.  Benzodiazepines on trial.

Authors:  P J Tyrer
Journal:  Br Med J (Clin Res Ed)       Date:  1984-04-14

Review 7.  Clinical relevance of pharmacokinetics.

Authors:  G Tognoni; C Bellantuono; M Bonati; M D'Incalci; M Gerna; R Latini; M Mandelli; M G Porro; E Riva
Journal:  Clin Pharmacokinet       Date:  1980 Mar-Apr       Impact factor: 6.447

8.  The use of benzodiazepines in depression.

Authors:  D A Johnson
Journal:  Br J Clin Pharmacol       Date:  1985       Impact factor: 4.335

9.  Antidepressant prescribing: a comparison between general practitioners and psychiatrists.

Authors:  M P Kerr
Journal:  Br J Gen Pract       Date:  1994-06       Impact factor: 5.386

10.  Patients' perceptions of psychotropic drugs.

Authors:  C G Helman
Journal:  J R Coll Gen Pract       Date:  1981-02
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