| Literature DB >> 7089564 |
R Langer, R J Linhardt, S Hoffberg, A K Larsen, C L Cooney, D Tapper, M Klein.
Abstract
The need to fully heparinize patients undergoing extracorporeal therapy often leads to hemorrhagic complications. To enable heparinization of only the extracorporeal circuit, a blood filter containing immobilized heparinase was developed. This filter degraded 99 percent of heparin's anticoagulant activity within minutes in both canine and human blood.Entities:
Mesh：
Substances：
Year: 1982 PMID： 7089564 DOI： 10.1126/science.7089564
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728