Literature DB >> 7089544

Diazepam impairs lateral position control in highway driving.

J F O'Hanlon, T W Haak, G J Blaauw, J B Riemersma.   

Abstract

Nine expert drivers operated an instrumented vehicle in tests over a highway at night after being treated with diazepam (5 and 10 milligrams), a placebo, and nothing. They reacted to 10 milligrams of diazepam with increased lateral position variability. Potentially dangerous impairment was inferred from the reactions of some subjects.

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Year:  1982        PMID： 7089544     DOI： 10.1126/science.7089544

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  42 in total

1.  Driving ability after acute and sub-chronic administration of levocetirizine and diphenhydramine: a randomized, double-blind, placebo-controlled trial.

Authors:  Joris C Verster; A Marit de Weert; Saskia I R Bijtjes; Mounir Aarab; Armand W A A van Oosterwijck; Erik J E Eijken; Marinus N Verbaten; Edmund R Volkerts
Journal:  Psychopharmacology (Berl)       Date:  2003-04-30       Impact factor: 4.530

2.  Methods for testing impairment of driving due to drugs.

Authors:  A Irving; W Jones
Journal:  Eur J Clin Pharmacol       Date:  1992       Impact factor: 2.953

3.  The challenges of interpreting residual effects of hypnotics.

Authors:  Thomas Roth
Journal:  Sleep       Date:  2011-10-01       Impact factor: 5.849

4.  Lapses of attention as outcome measure of the on-the-road driving test.

Authors:  Joris C Verster; Adriana C Bervoets; Suzanne de Klerk; Thomas Roth
Journal:  Psychopharmacology (Berl)       Date:  2013-08-24       Impact factor: 4.530

Review 5.  Residual effects of hypnotics: epidemiology and clinical implications.

Authors:  Annemiek Vermeeren
Journal:  CNS Drugs       Date:  2004       Impact factor: 5.749

6.  A comparative study of acute and subchronic effects of dothiepin, fluoxetine and placebo on psychomotor and actual driving performance.

Authors:  J G Ramaekers; N D Muntjewerff; J F O'Hanlon
Journal:  Br J Clin Pharmacol       Date:  1995-04       Impact factor: 4.335

Review 7.  Medication use and the risk of motor vehicle collisions among licensed drivers: A systematic review.

Authors:  Toni M Rudisill; Motao Zhu; George A Kelley; Courtney Pilkerton; Brandon R Rudisill
Journal:  Accid Anal Prev       Date:  2016-08-29

8.  Acute and subchronic effects of the H1-histamine receptor antagonist ebastine in 10, 20 and 30 mg dose, and triprolidine 10 mg on car driving performance.

Authors:  K A Brookhuis; G De Vries; D De Waard
Journal:  Br J Clin Pharmacol       Date:  1993-07       Impact factor: 4.335

9.  Effects of diazepam on behavior and dopamine-containing substantia nigra units in freely moving cats.

Authors:  M E Trulson
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

Review 10.  Psychoactive medication and traffic safety.

Authors:  Joris C Verster; Monique A J Mets
Journal:  Int J Environ Res Public Health       Date:  2009-03-10       Impact factor: 3.390
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