| Literature DB >> 7086156 |
R W Knowles, Y Bai, G L Daniels, W Watkins.
Abstract
A monoclonal antibody was produced which binds specifically to Type 2 H antigen of the ABO blood group system. The antibody, H11, is an IgM molecule which reacts by direct agglutination of red cells with the same pattern as other anti H reagents such as Ulex europaeus lectin. The specificity was determined by inhibition and adsorption with chemically defined oligosaccharides. H11 also reacted with poly (glycosyl) ceramide purified from group 0 red cells and glycoprotein H purified from human stomach mucosa and meconium. H11 differs from Ulex lectin, however, in that it was not inhibited by saliva from ABH secretor individuals or by glycoprotein H purified from human ovarian cysts or submaxillary glands.Entities:
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Year: 1982 PMID： 7086156 DOI： 10.1111/j.1744-313x.1982.tb00965.x
Source DB: PubMed Journal: J Immunogenet ISSN： 0305-1811