Literature DB >> 7085430

Interaction of serotonin with vagal- and ACh-induced bronchoconstriction in canine lungs.

J R Sheller, M J Holtzman, B E Skoogh, J A Nadel.   

Abstract

The bronchoconstrictor response to electrical stimulation of the peripheral ends of both cut cervical vagus nerves was potentiated by serotonin aerosols in 10 experiments in 7 anesthetized dogs. The bronchoconstrictor response to acetylcholine (ACh) aerosols was unchanged after serotonin. We conclude that serotonin acts at the level of the parasympathetic ganglia or the postganglionic nerve terminal to potentiate the bronchoconstrictor response to vagal stimulation.

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Year:  1982        PMID: 7085430     DOI: 10.1152/jappl.1982.52.4.964

Source DB:  PubMed          Journal:  J Appl Physiol Respir Environ Exerc Physiol        ISSN: 0161-7567


  9 in total

1.  Human responses to inhaled capsaicin are not inhibited by granisetron.

Authors:  N B Choudry; J R McEwan; E A Lavender; A J Williams; R W Fuller
Journal:  Br J Clin Pharmacol       Date:  1991-03       Impact factor: 4.335

2.  Receptors mediating the effects of 5-hydroxytryptamine on the tracheal vasculature and smooth muscle of sheep.

Authors:  S E Webber; R O Salonen; J G Widdicombe
Journal:  Br J Pharmacol       Date:  1990-01       Impact factor: 8.739

3.  The effects of the 5 HT2 antagonist ketanserin in adult atopic asthma.

Authors:  D J Stott; J A Roberts; N C Thomson; S G Ball
Journal:  Eur J Clin Pharmacol       Date:  1988       Impact factor: 2.953

4.  Proceedings of the British Pharmacological Society, University of Cambridge, 6th-8th April, 1983. Abstracts.

Authors: 
Journal:  Br J Pharmacol       Date:  1983-06       Impact factor: 8.739

5.  Assessment of induced bronchoconstriction in anesthetized cats by the end-inflation occlusion method.

Authors:  P Baconnier; R Vahi-Maqueda; M Saetta; B Hasegawa; J Milic-Emili; N Pride
Journal:  Lung       Date:  1989       Impact factor: 2.584

6.  An ubiquitous modulating function of rabbit tracheal epithelium: degradation of tachykinins.

Authors:  K Inoue; Y Sakai; I Homma
Journal:  Br J Pharmacol       Date:  1992-02       Impact factor: 8.739

7.  A pharmacological analysis of receptors mediating the excitatory response to 5-hydroxytryptamine in the guinea-pig isolated trachea.

Authors:  A Lucchelli; M G Santagostino-Barbone; A Barbieri; M Tonini
Journal:  Br J Pharmacol       Date:  1994-07       Impact factor: 8.739

8.  Modulation of capsaicin induced airway reflexes in humans: effect of monoamine oxidase inhibition.

Authors:  N B Choudry; J Studham; D Harland; R W Fuller
Journal:  Br J Clin Pharmacol       Date:  1993-02       Impact factor: 4.335

9.  Autonomic responses of the isolated, innervated trachea of the guinea-pig: interaction with autonomic drugs, histamine and 5-hydroxytryptamine.

Authors:  D J McCaig
Journal:  Br J Pharmacol       Date:  1986-05       Impact factor: 8.739

  9 in total

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