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Literature DB >> 7084406

3, 5-Dibromo-2'-chloro-4'-isothiocyanatosalicylanilide, a potent anthelmintic.

J C Katiyar, P K Visen, S Gupata, A B Sen, S K Dubey, S Sharma.

Abstract

The compound, 3, 5-dibromo-2'-chloro-4'-isothiocyanatosalicylanilide, has been tested against various nematode and cestode parasites in experimental and domestic animals. It shoved 100% activity against Ancylostoma ceylanicum, A tubaeformis, Syphacia obvelata, ascaridia galli, Toxocara spp., Toxascaris sp., Gnathostoma spinigerum, Hymenolepis nana, Raillietina spp. and Taenia spp. in doses 25-70 mg/kg given in single or multiple administrations.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1982 PMID： 7084406 DOI： 10.1007/BF01952636

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

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References

11 in total

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5. Experimental studies with Nippostrongylus brasiliensis on factors modifying therapeutic efficacy of anthelmintics in rats.

Authors: A Misra; J C Katiyar; A B Sen
Journal: Indian J Exp Biol Date: 1980-08 Impact factor: 0.818

3, 5-Dibromo-2'-chloro-4'-isothiocyanatosalicylanilide, a potent anthelmintic.

1. Clinical trial of mebendazole, a broad-spectrum anthelminthic.

Review 2. Helminthiasis in India. Part I: Prevalence and geographical distribution: soil transmitted nematodes.

3. The use of mebendazole as a broad-spectrum anthelmintic in Rhodesia.

4. [Therapeutic action of mebendazole (R 17,635) in multiple-parasitized patients. Preliminary results].

5. Experimental studies with Nippostrongylus brasiliensis on factors modifying therapeutic efficacy of anthelmintics in rats.

6. Anticestode activity of 3,5-dibromo-2'-chlorosalicylanilide-4'-isothiocyanate--a preliminary report.

7. Mebendazole.

8. Screening of cesticidal compounds on a tapeworm Hymenolepis nana in vitro.

9. Efficacy of seven anthelmintics against Ancylostoma ceylanicum in the golden hamster, Mesocricetus auratus.

10. Mebendazole in the treatment of taeniasis solium and taeniasis saginata.