Literature DB >> 1131521

Clinical trial of mebendazole, a broad-spectrum anthelminthic.

J G Hutchison, N M Johnston, M V Plevey, I Thangkhiew, C Aidney.   

Abstract

Eighty-five children aged 5-14 years who were infested with worms were treated with mebendazole 100 mg twice daily for three days. The percentage cure rates were ascaris 100%, trichuris 94%, hookworm 82%, and hymenolepis 39%. The drug was well tolerated and with its broad activity should be very useful in treating those with multiple infestations.

Entities:  

Mesh：

Substances：

Year:  1975        PMID： 1131521      PMCID： PMC1681918          DOI： 10.1136/bmj.2.5966.309

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  3 in total

1.  Mebendazole in enterobiasis. Radiochemical and pilot clinical study in 1,278 subjects.

Authors:  J P Brugmans; D C Thienpont; I van Wijngaarden; O F Vanparijs; V L Schuermans; H L Lauwers
Journal:  JAMA       Date:  1971-07-19       Impact factor: 56.272

2.  Further observations on the formol-ether concentration technique for faecal parasites.

Authors:  A V Allen; D S Ridley
Journal:  J Clin Pathol       Date:  1970-09       Impact factor: 3.411

3.  Survey of intestinal pathogens from immigrant children.

Authors:  R G Thompson; J G Hutchison; N M Johnston
Journal:  Br Med J       Date:  1972-03-04
  3 in total
  8 in total

1.  Randomized clinical study of five days apostrophe therapy with mebendazole compared to quinacrine in the treatment of symptomatic giardiasis in children.

Authors:  Roberto Canete; Angel A Escobedo; Maria E Gonzalez; Pedro Almirall
Journal:  World J Gastroenterol       Date:  2006-10-21       Impact factor: 5.742

2.  Nippostronglylus brasiliensis infection in the rat: effect of iron and protein deficiency and dexamethasone on the efficacy of benzimidazole anthelmintics.

Authors:  V M Duncombe; T D Bolin; A E Davis; J D Kelly
Journal:  Gut       Date:  1977-11       Impact factor: 23.059

3.  Mebendazole in the treatment of helminthiasis.

Authors:  S K Seah
Journal:  Can Med Assoc J       Date:  1976-10-23       Impact factor: 8.262

4.  3, 5-Dibromo-2'-chloro-4'-isothiocyanatosalicylanilide, a potent anthelmintic.

Authors:  J C Katiyar; P K Visen; S Gupata; A B Sen; S K Dubey; S Sharma
Journal:  Experientia       Date:  1982-04-15

5.  Nippostrongylus brasiliensis infection in the rat: effect of iron and protein deficiency on the anthelmintic efficacy of mebendazole, pyrantel, piperazine, and levamisole.

Authors:  V M Duncombe; T D Bolin; A E Davis; M R Fagan; J D Kelly
Journal:  Gut       Date:  1979-04       Impact factor: 23.059

6.  Mebendazole compared with secnidazole in the treatment of adult giardiasis: a randomised, no-inferiority, open clinical trial.

Authors:  Pedro Almirall; Angel A Escobedo; Idalia Ayala; Maydel Alfonso; Yohana Salazar; Roberto Cañete; Sergio Cimerman; Martha Galloso; Ilmaems Olivero; Maytee Robaina; Karen Tornés
Journal:  J Parasitol Res       Date:  2011-11-20

7.  Effectiveness and Tolerability of 3-Day Mebendazole Treatment of Giardia duodenalis Infection in Adults and Children: Two Prospective, Open-Label Phase IV Trials.

Authors:  Roberto Cañete; Katia Brito; Inara Brito; Abel Semper; Maria Elena Gonzalez
Journal:  Curr Ther Res Clin Exp       Date:  2018-11-30

8.  Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update.

Authors:  Jong-Yil Chai; Bong-Kwang Jung; Sung-Jong Hong
Journal:  Korean J Parasitol       Date:  2021-06-21       Impact factor: 1.341
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.