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Literature DB >> 708385

Haem degradation in abnormal haemoglobins.

Abstract

The coupled oxidation of certain abnormal haemoglobins leads to different bile-pigment isomer distributions from that of normal haemoglobin. The isomer pattern may be correlated with the structure of the abnormal haemoglobin in the neighbourhood of the haem pocket. This is support for haem degradation by an intramolecular reaction.

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Year: 1978 PMID： 708385 PMCID： PMC1185868 DOI： 10.1042/bj1730985

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

10 in total

Review 1. The enzymatic formation of bilirubin.

Authors: R Schmid; A F McDonagh
Journal: Ann N Y Acad Sci Date: 1975-04-15 Impact factor: 5.691

2. HAEM catabolism and coupled oxidation of haemproteins.

Authors: P O. 'Carra; E Colleran
Journal: FEBS Lett Date: 1969-11-29 Impact factor: 4.124

3. Stereospecific haem cleavage. A model for the formation of bile-pigment isomers in vivo and in vitro.

Authors: S B Brown
Journal: Biochem J Date: 1976-10-01 Impact factor: 3.857

4. The electronic structure of the haem iron in haemoglobin Zurich beta 63his-arg.

Authors: K H Winterhalter; E E Di Iorio; J G Beetlestone; J B Kushimo; H Uebelhack; H Eicher; A Mayer
Journal: J Mol Biol Date: 1972-10-14 Impact factor: 5.469

5. The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase.

Authors: R Tenhunen; H S Marver; R Schmid
Journal: Proc Natl Acad Sci U S A Date: 1968-10 Impact factor: 11.205

6. Haemoglobin catabolism: the role of ferrihaems in studies of the degradation pathway.

Authors: N A Brown; R F King; M E Shillcock; S B Brown
Journal: Biochem J Date: 1974-01 Impact factor: 3.857

7. The meso-reactivity of porphyrins and related compounds. VI. Oxidative cleavage of the haem system. The four isomeric biliverdins of the IX series.

Authors: R Bonnett; A F McDonagh
Journal: J Chem Soc Perkin 1 Date: 1973

4 in total

1. Theoretical prediction and experimental measurement of the bile-pigment isomer pattern obtained from degradation of catalase haem.

Authors: N J Brindle; A C North; S B Brown
Journal: Biochem J Date: 1986-05-15 Impact factor: 3.857

Haem degradation in abnormal haemoglobins.

Review 1. The enzymatic formation of bilirubin.

2. HAEM catabolism and coupled oxidation of haemproteins.

3. Stereospecific haem cleavage. A model for the formation of bile-pigment isomers in vivo and in vitro.

4. The electronic structure of the haem iron in haemoglobin Zurich beta 63his-arg.

5. The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase.

6. Haemoglobin catabolism: the role of ferrihaems in studies of the degradation pathway.

7. The meso-reactivity of porphyrins and related compounds. VI. Oxidative cleavage of the haem system. The four isomeric biliverdins of the IX series.

8. Structural investigations of modified haemoglobins by nuclear magnetic resonance spectroscopy.

9. Molecular pathology of human haemoglobin.

Review 10. Structure and mechanism of haemoglobin.

1. Theoretical prediction and experimental measurement of the bile-pigment isomer pattern obtained from degradation of catalase haem.

2. Haem disorder in reconstituted human haemoglobin.

3. Haem degradation in human haemoglobin in vitro. Separation of the contribution of the alpha- and beta-subunits.

4. Formation of bile pigments by coupled oxidation of cobalt-substituted haemoglobin and myoglobin.