Literature DB >> 4821396

Haemoglobin catabolism: the role of ferrihaems in studies of the degradation pathway.

N A Brown, R F King, M E Shillcock, S B Brown.   

Abstract

The importance of ferrihaem aggregation in studies of haemoglobin catabolism is assessed in the light of recent work. Experimental evidence is put forward suggesting that monomeric ferrihaems are degraded much more readily than dimeric species. This may offer an alternative explanation for the apparent ;apoprotein catalysis' recently observed.

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Year:  1974        PMID： 4821396      PMCID： PMC1166093          DOI： 10.1042/bj1370135

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  12 in total

1.  Bile pigment formation in vitro from haematin and haem derivatives.

Authors:  J E KENCH
Journal:  Biochem J       Date:  1954-04       Impact factor: 3.857

Review 2.  The degradation of haem by mammals and its excretion as conjugated bilirubin.

Authors:  G H Lathe
Journal:  Essays Biochem       Date:  1972       Impact factor: 8.000

3.  Degradation of haem compounds to bile pigments.

Authors:  C H Gray; D C Nicholson; G Tipton
Journal:  Nat New Biol       Date:  1972-09-06

4.  Enzymatic degradation of heme. Oxygenative cleavage requiring cytochrome P-450.

Authors:  R Tenhunen; H Marver; N R Pimstone; W F Trager; D Y Cooper; R Schmid
Journal:  Biochemistry       Date:  1972-04-25       Impact factor: 3.162

5.  Catalatic activity of iron(3)-centred catalysts. Role of dimerization in the catalytic action of ferrihaems.

Authors:  S B Brown; T C Dean; P Jones
Journal:  Biochem J       Date:  1970-05       Impact factor: 3.857

6.  Aggregation of ferrihaems. Dimerization and protolytic equilibria of protoferrihaem and deuteroferrihaem in aqueous solution.

Authors:  S B Brown; T C Dean; P Jones
Journal:  Biochem J       Date:  1970-05       Impact factor: 3.857

7.  Infrared evidence for an oxo-bridged (Fe-O-Fe) haemin dimer.

Authors:  S B Brown; P Jones; I R Lantzke
Journal:  Nature       Date:  1969-08-30       Impact factor: 49.962

8.  Oxidation of deuteroferrihaem by hydrogen peroxide.

Authors:  P Jones; K Prudhoe; T Robson
Journal:  Biochem J       Date:  1973-10       Impact factor: 3.857

9.  Non-enzymic nature of the pyridine haemochrome-cleaving activity of mammalian tissue extracts ('haem alpha-methenyl oxygenase').

Authors:  E Colleran; P O Carra
Journal:  Biochem J       Date:  1970-10       Impact factor: 3.857

10.  Solution structures of ferrihaem in some dipolar aprotic solvents and their binary aqueous mixtures.

Authors:  S B Brown; I R Lantzke
Journal:  Biochem J       Date:  1969-11       Impact factor: 3.857
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  8 in total

1.  Quantitation of heme oxygenase 1: heme titration increases yield of purified protein.

Authors:  Warren J Huber; Wayne L Backes
Journal:  Anal Biochem       Date:  2007-10-11       Impact factor: 3.365

2.  The structure of haem in pyridine/water mixtures and its implication in studies of haem catabolism.

Authors:  S B Brown; R F King
Journal:  Biochem J       Date:  1976-02-01       Impact factor: 3.857

3.  Stereospecific haem cleavage. A model for the formation of bile-pigment isomers in vivo and in vitro.

Authors:  S B Brown
Journal:  Biochem J       Date:  1976-10-01       Impact factor: 3.857

4.  The mechanism of haem catabolism. A study of haem breakdown in spleen microsomal fraction and in a model system by 18O labelling and metal substitution.

Authors:  R F King; S B Brown
Journal:  Biochem J       Date:  1978-07-15       Impact factor: 3.857

5.  Haem degradation in abnormal haemoglobins.

Authors:  S B Brown; J C Docherty
Journal:  Biochem J       Date:  1978-09-01       Impact factor: 3.857

6.  Heme Inhibition of [delta]-Aminolevulinic Acid Synthesis Is Enhanced by Glutathione in Cell-Free Extracts of Chlorella.

Authors:  J. D. Weinstein; R. W. Howell; R. D. Leverette; S. Y. Grooms; P. S. Brignola; S. M. Mayer; S. I. Beale
Journal:  Plant Physiol       Date:  1993-02       Impact factor: 8.340

7.  Haem disorder in reconstituted human haemoglobin.

Authors:  J C Docherty; S B Brown
Journal:  Biochem J       Date:  1982-12-01       Impact factor: 3.857

8.  Equilibrium and kinetic studies of the aggregation of porphyrins in aqueous solution.

Authors:  S B Brown; M Shillcock; P Jones
Journal:  Biochem J       Date:  1976-02-01       Impact factor: 3.766
  8 in total

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