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Literature DB >> 7082293

The identification of the weak oestrogen equol [7-hydroxy-3-(4'-hydroxyphenyl)chroman] in human urine.

M Axelson, D N Kirk, R D Farrant, G Cooley, A M Lawson, K D Setchell.

Abstract

The identification (by gas chromatography-mass spectrometry and n.m.r.) for the first time of the weak oestrogen equol [7-hydroxy-3-(4'-hydroxyphenyl)chroman] in human urine is described. Preliminary results of its quantitative excretion in urine are reported and the potential significance of the occurrence of this compound is discussed.

Entities: Chemical Species

Mesh：

Substances：

Year: 1982 PMID： 7082293 PMCID： PMC1163650 DOI： 10.1042/bj2010353

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

19 in total

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Authors: R B BRADBURY; D E WHITE
Journal: Vitam Horm Date: 1954 Impact factor: 3.421

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Authors: R H COMMON; L AINSWORTH
Journal: Biochim Biophys Acta Date: 1961-10-28

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Authors: W KLYNE; A A WRIGHT
Journal: Biochem J Date: 1957-05 Impact factor: 3.857

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Authors: B Spiegelhalder; G Röhle; L Siekmann; H Breuer
Journal: J Steroid Biochem Date: 1976-10 Impact factor: 4.292

5. An in vitro study of formononetin and biochanin A metabolism in rumen fluid from sheep.

Authors: A Nilsson; J L Hill; H L Davids
Journal: Biochim Biophys Acta Date: 1967-10-09

6. Metabolism of oestrogenic isoflavones in sheep.

Authors: T J Batterham; N K Hart; J A Lamberton
Journal: Nature Date: 1965-05-01 Impact factor: 49.962

7. The excretion of lignans in rats -- evidence for an intestinal bacterial source for this new group of compounds.

Authors: M Axelson; K D Setchell
Journal: FEBS Lett Date: 1981-01-26 Impact factor: 4.124

8. Analysis of unconjugated steroids in plasma by liquid-gel chromatography and glass capillary gas chromatography mass spectrometry.

Authors: M Axelson; J Sjövall
Journal: J Steroid Biochem Date: 1977-06 Impact factor: 4.292

9. Lignans in man and in animal species.

Authors: K D Setchell; A M Lawson; F L Mitchell; H Adlercreutz; D N Kirk; M Axelson
Journal: Nature Date: 1980-10-23 Impact factor: 49.962

10. The definitive identification of the lignans trans-2,3-bis(3-hydroxybenzyl)-gamma-butyrolactone and 2,3-bis(3-hydroxybenzyl)butane-1,4-diol in human and animal urine.

Authors: K D Setchell; A M Lawson; E Conway; N F Taylor; D N Kirk; G Cooley; R D Farrant; S Wynn; M Axelson
Journal: Biochem J Date: 1981-08-01 Impact factor: 3.857

29 in total

Review 1. Equol: history, chemistry, and formation.

Authors: Kenneth D R Setchell; Carlo Clerici
Journal: J Nutr Date: 2010-06-02 Impact factor: 4.798

2. Training in metabolomics research. I. Designing the experiment, collecting and extracting samples and generating metabolomics data.

Authors: Stephen Barnes; H Paul Benton; Krista Casazza; Sara J Cooper; Xiangqin Cui; Xiuxia Du; Jeffrey Engler; Janusz H Kabarowski; Shuzhao Li; Wimal Pathmasiri; Jeevan K Prasain; Matthew B Renfrow; Hemant K Tiwari
Journal: J Mass Spectrom Date: 2016-07 Impact factor: 1.982

Review 3. The effect of phytoestrogens on the female genital tract.

Authors: J L Burton; M Wells
Journal: J Clin Pathol Date: 2002-06 Impact factor: 3.411

Review 4. Isoflavones: estrogenic activity, biological effect and bioavailability.

Authors: Daniela Cristina Vitale; Cateno Piazza; Barbara Melilli; Filippo Drago; Salvatore Salomone
Journal: Eur J Drug Metab Pharmacokinet Date: 2013-03 Impact factor: 2.441

5. The chemopreventive action of equol enantiomers in a chemically induced animal model of breast cancer.

Authors: Nadine M Brown; Carrie A Belles; Stephanie L Lindley; Linda D Zimmer-Nechemias; Xueheng Zhao; David P Witte; Mi-Ok Kim; Kenneth D R Setchell
Journal: Carcinogenesis Date: 2010-01-28 Impact factor: 4.944

6. Antioxidant effect of a phytoestrogen equol on cultured muscle cells of embryonic broilers.

Authors: Xiao-Jing Wei; Jing Wu; Ying-Dong Ni; Li-Zhi Lu; Ru-Qian Zhao
Journal: In Vitro Cell Dev Biol Anim Date: 2011-11-16 Impact factor: 2.416

7. The pharmacokinetic behavior of the soy isoflavone metabolite S-(-)equol and its diastereoisomer R-(+)equol in healthy adults determined by using stable-isotope-labeled tracers.

Authors: Kenneth Dr Setchell; Xueheng Zhao; Pinky Jha; James E Heubi; Nadine M Brown
Journal: Am J Clin Nutr Date: 2009-08-26 Impact factor: 7.045