Literature DB >> 7081355

The role of cellular proliferation in an experimental model of massive periretinal proliferation.

D M Fastenberg, K R Diddie, K Dorey, S J Ryan.   

Abstract

Transplantation of from 10,000 to 750,000 autologous and homologous dermal fibroblasts into the vitreous cavity of rabbit eyes resulted in identical clinical findings leading to massive periretinal proliferation. A dose-response relationship between the number of cells injected and the extent of retinal traction that developed was established. The second phase of the experiment evaluated the effects of formalin and cobalt irradiation on the fibroblasts' ability to cause traction retinal detachment. Cell proliferation or the attainment of a critical mass of living cells was necessary for the development of traction retinal detachment.

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Year:  1982        PMID： 7081355     DOI： 10.1016/s0002-9394(14)77370-2

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN： 0002-9394            Impact factor:   5.258


  35 in total

1.  Evaluation of radiation therapy for experimental proliferative vitreoretinopathy in rabbits.

Authors:  S Kuriyama; T Ohuchi; N Yoshimura; Y Honda; M Hiraoka; M Abe
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1990       Impact factor: 3.117

2.  The lack of an effect of intraocular steroids on irradiated fibroblasts in experimental proliferative vitreoretinopathy.

Authors:  D B Chandler; T Hida; G Rozakis; V S Forbes; R Machemer
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1992       Impact factor: 3.117

3.  The novel use of decorin in prevention of the development of proliferative vitreoretinopathy (PVR).

Authors:  Khaled Nassar; Julia Lüke; Matthias Lüke; Mahmoud Kamal; Effat Abd El-Nabi; Mahmoud Soliman; Martin Rohrbach; Salvatore Grisanti
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2011-07-07       Impact factor: 3.117

4.  Role of TGF-beta in proliferative vitreoretinal diseases and ROCK as a therapeutic target.

Authors:  Takeshi Kita; Yasuaki Hata; Ryoichi Arita; Shuhei Kawahara; Muneki Miura; Shintaro Nakao; Yasutaka Mochizuki; Hiroshi Enaida; Yoshinobu Goto; Hiroaki Shimokawa; Ali Hafezi-Moghadam; Tatsuro Ishibashi
Journal:  Proc Natl Acad Sci U S A       Date:  2008-10-24       Impact factor: 11.205

5.  Connective tissue growth factor as a mediator of intraocular fibrosis.

Authors:  Shikun He; Youxin Chen; Rima Khankan; Ernesto Barron; Richard Burton; Danhong Zhu; Stephen J Ryan; Noelynn Oliver; David R Hinton
Journal:  Invest Ophthalmol Vis Sci       Date:  2008-04-30       Impact factor: 4.799

6.  Development of traction retinal detachments following intravitreal injections of retinal Muller and pigment epithelial cells.

Authors:  M A Peters; J M Burke; M Clowry; G W Abrams; G A Williams
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1986       Impact factor: 3.117

7.  Antifibrotic and uveitogenic properties of gamma interferon in the rabbit eye.

Authors:  L M Hjelmeland; J W Li; C A Toth; M B Landers
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1992       Impact factor: 3.117

8.  Measurement of cellular proliferation within the vitreous during experimental proliferative vitreoretinopathy.

Authors:  C M Yang; K R Olsen; E Hernandez; S W Cousins
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1992       Impact factor: 3.117

9.  A novel function of p53: a gatekeeper of retinal detachment.

Authors:  Hetian Lei; Marc-Andre Rheaume; Jing Cui; Shizuo Mukai; David Maberley; Arif Samad; Joanne Matsubara; Andrius Kazlauskas
Journal:  Am J Pathol       Date:  2012-09       Impact factor: 4.307

10.  Daunorubicin treatment in a refined experimental model of proliferative vitreoretinopathy.

Authors:  J A Khawly; P Saloupis; D L Hatchell; R Machemer
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1991       Impact factor: 3.117
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