Literature DB >> 7079183

Comparative analysis of nucleic acid sequences by their general constraints.

D J Lipman, J Maizel.   

Abstract

We describe two measures of a nucleic acid sequence, derived from Information Theory, which characterize the constraints toward nonuniform base composition, and the constraints on the ordering of the bases. These two measures distinguish extra-chromosomal coding sequences from all other coding sequences examined. The two measures separate eukaryotic coding sequences into two groups: those with introns and those without introns. We have also found a relationship between the general constraints of a subsequence and its degree of conservation in related genes.

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Year:  1982        PMID： 7079183      PMCID： PMC320646          DOI： 10.1093/nar/10.8.2723

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  6 in total

1.  Enhanced graphic matrix analysis of nucleic acid and protein sequences.

Authors:  J V Maizel; R P Lenk
Journal:  Proc Natl Acad Sci U S A       Date:  1981-12       Impact factor: 11.205

2.  Why genes in pieces?

Authors:  W Gilbert
Journal:  Nature       Date:  1978-02-09       Impact factor: 49.962

3.  The structure and evolution of the human beta-globin gene family.

Authors:  A Efstratiadis; J W Posakony; T Maniatis; R M Lawn; C O'Connell; R A Spritz; J K DeRiel; B G Forget; S M Weissman; J L Slightom; A E Blechl; O Smithies; F E Baralle; C C Shoulders; N J Proudfoot
Journal:  Cell       Date:  1980-10       Impact factor: 41.582

4.  DNA sequencing and gene structure.

Authors:  W Gilbert
Journal:  Science       Date:  1981-12-18       Impact factor: 47.728

5.  Identification of common molecular subsequences.

Authors:  T F Smith; M S Waterman
Journal:  J Mol Biol       Date:  1981-03-25       Impact factor: 5.469

6.  Base substitutions, length differences and DNA strand asymmetries in the human G gamma and A gamma fetal globin gene region.

Authors:  O Smithies; W R Engels; J R Devereux; J L Slightom; S Shen
Journal:  Cell       Date:  1981-11       Impact factor: 41.582
  6 in total
  9 in total

1.  Informational parameters and randomness of mitochondrial DNA.

Authors:  M I Granero-Porati; A Porati
Journal:  J Mol Evol       Date:  1988       Impact factor: 2.395

2.  Codon preference and primary sequence structure in protein-coding regions.

Authors:  S Tavaré; B Song
Journal:  Bull Math Biol       Date:  1989       Impact factor: 1.758

3.  Nonuniformity of nucleotide substitution rates in molecular evolution: computer simulation and analysis of 5S ribosomal RNA sequences.

Authors:  C L Manske; D J Chapman
Journal:  J Mol Evol       Date:  1987       Impact factor: 2.395

4.  Strong doublet preferences in nucleotide sequences and DNA geometry.

Authors:  R Nussinov
Journal:  J Mol Evol       Date:  1984       Impact factor: 2.395

5.  Signal search analysis: a new method to localize and characterize functionally important DNA sequences.

Authors:  P Bucher; B Bryan
Journal:  Nucleic Acids Res       Date:  1984-01-11       Impact factor: 16.971

6.  Sequence homologies in the protamine gene family of rainbow trout.

Authors:  J M Aiken; D McKenzie; H Z Zhao; J C States; G H Dixon
Journal:  Nucleic Acids Res       Date:  1983-07-25       Impact factor: 16.971

7.  A transcriptional barrier to expression of cloned toxin genes of the linear plasmid k1 of Kluyveromyces lactis: evidence that native k1 has novel promoters.

Authors:  M A Romanos; A Boyd
Journal:  Nucleic Acids Res       Date:  1988-08-11       Impact factor: 16.971

8.  Hierarchical analysis of influenza A hemagglutinin gene sequences.

Authors:  D J Lipman; T F Smith; R J Beckman; M S Waterman
Journal:  Nucleic Acids Res       Date:  1982-09-11       Impact factor: 16.971

9.  Nucleotide sequence and transcription analysis of a linear DNA plasmid associated with the killer character of the yeast Kluyveromyces lactis.

Authors:  M J Stark; A J Mileham; M A Romanos; A Boyd
Journal:  Nucleic Acids Res       Date:  1984-08-10       Impact factor: 16.971
  9 in total

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