Surgery for ventricular tachycardia: efficacy of left ventricular aneurysm resection compared with operation guided by electrical activation mapping.

Sixty-five patients underwent surgery for recurrent ventricular tachyarrhythmias. The 32 patients in group 1 underwent simple left ventricular aneurysm resection. The 33 patients in group 2 underwent myocardial resection or incision guided by intraoperative mapping of the electrical activation sequence. The clinical, hemodynamic and angiographic characteristics of the two groups were similar. Although actuarial survival in the two groups was similar through 24 months, late attrition in group 1 patients has left only 21 +/- 13% (+/- SEM) alive by life-table analysis at 94 months. Arrhythmia recurrence has been greater in group 1 than in group 2. In group 1, 50 +/- 9% of patients at risk at 3 months had recurrences by actuarial analysis. In group 2, only 13 +/- 6% at 1 month, 17 +/- 7% at 3 months and 29 +/- 9% at 24 months relapsed. Death was caused by ventricular tachyarrhythmias in 12 of the 17 patients (71%) who died in group 1, but only three of 12 (25%) who died in group 2. We conclude that surgery of the left ventricle, guided and modified by intraoperative mapping of the electrical activation sequence, frequently eliminates ventricular tachyarrhythmias and may be more effective than blind resection of left ventricular aneurysm.