Literature DB >> 7073999

Activity of serum cytidine deaminase during pregnancy.

D D Jones, S Bahijri, E L Roberts, G F Williams.   

Abstract

A simple and reliable method for the estimation of cytidine deaminase (cytidine aminohydrolase; EC 3.5.4.5) activity in pregnancy serum is described. This enzyme does not require magnesium for activation and is also more stable than deoxycytidylate deaminase (dCMP deaminase, dCMP aminohydrolase; EC 3.5.4.12). There was excellent correlation between the two enzymes (r = 0.92). Both enzymes showed increased activity in abnormal pregnancy. Both enzymes activities were found to be similar in 1305 maternal serum samples and therefore due to the simplicity of cytidine deaminase estimation it is recommended for the screening of large numbers of antenatal sera for abnormal pregnancies.

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Year:  1982        PMID： 7073999     DOI： 10.1111/j.1471-0528.1982.tb04703.x

Source DB:  PubMed          Journal:  Br J Obstet Gynaecol        ISSN： 0306-5456


  6 in total

Review 1.  The Emerging Role of Cytidine Deaminase in Human Diseases: A New Opportunity for Therapy?

Authors:  Audrey Frances; Pierre Cordelier
Journal:  Mol Ther       Date:  2019-12-06       Impact factor: 11.454

2.  Serum cytidine deaminase as a laboratory test for acute inflammation in rheumatoid arthritis.

Authors:  I M Chalmers; G T Thomson; P Desjardins
Journal:  Ann Rheum Dis       Date:  1988-02       Impact factor: 19.103

3.  Serum cytidine deaminase levels after withdrawal of non-steroidal anti-inflammatory treatment in rheumatoid arthritis.

Authors:  P W Thompson; J R Kirwan; D D Jones; H L Currey
Journal:  Ann Rheum Dis       Date:  1988-04       Impact factor: 19.103

4.  Cytidine deaminase activity in synovial fluid of patients with rheumatoid arthritis: relation to lactoferrin, acidosis, and cartilage proteoglycan release.

Authors:  B Månsson; P Geborek; T Saxne; S Björnsson
Journal:  Ann Rheum Dis       Date:  1990-08       Impact factor: 19.103

5.  Cytidine deaminase activity as a measure of acute inflammation in rheumatoid arthritis.

Authors:  P W Thompson; D D Jones; H L Currey
Journal:  Ann Rheum Dis       Date:  1986-01       Impact factor: 19.103

6.  Expression of two proopiomelanocortin genes in the pituitary gland of Xenopus laevis: complete structures of the two preprohormones.

Authors:  G J Martens
Journal:  Nucleic Acids Res       Date:  1986-05-12       Impact factor: 16.971
  6 in total

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