Literature DB >> 7073597

Biopsy of human olfactory mucosa. An instrument and a technique.

M A Lovell, B W Jafek, D T Moran, J C Rowley.   

Abstract

We have developed an instrument that obtains small biopsy specimens of human olfactory mucosa suitable for electron microscopy. Following local anesthesia of the patient, the instrument is introduced through the naris and advanced 60 to 70 mm between the septum and middle turbinate. The cutting edge is pressed against the olfactory area and then is withdrawn with the mucosal specimen. This procedure has been performed successfully on 12 people with no substantial adverse effects. We have provided the indications for the use of this technique and its possible applications.

Entities:  

Mesh：

Year:  1982        PMID： 7073597     DOI： 10.1001/archotol.1982.00790520047013

Source DB:  PubMed          Journal:  Arch Otolaryngol        ISSN： 0003-9977


  15 in total

1.  Human nasal olfactory epithelium as a dynamic marker for CNS therapy development.

Authors:  Rita Sattler; Yoko Ayukawa; Luke Coddington; Akira Sawa; David Block; Richard Chipkin; Jeffrey D Rothstein
Journal:  Exp Neurol       Date:  2011-09-16       Impact factor: 5.330

2.  Olfactory epithelium amyloid-beta and paired helical filament-tau pathology in Alzheimer disease.

Authors:  Steven E Arnold; Edward B Lee; Paul J Moberg; Lauren Stutzbach; Hala Kazi; Li-Ying Han; Virginia M Y Lee; John Q Trojanowski
Journal:  Ann Neurol       Date:  2010-04       Impact factor: 10.422

3.  Altered olfactory epithelial structure and function in feline models of mucopolysaccharidoses I and VI.

Authors:  Fritz W Lischka; George Gomez; Karen K Yee; Luba Dankulich-Nagrudny; Leen Lo; Mark E Haskins; Nancy E Rawson
Journal:  J Comp Neurol       Date:  2008-11-20       Impact factor: 3.215

Review 4.  The human olfactory mucosa.

Authors:  Pedro Alberto Escada; Carlos Lima; José Madeira da Silva
Journal:  Eur Arch Otorhinolaryngol       Date:  2009-11       Impact factor: 2.503

5.  Anatomy and cellular constituents of the human olfactory mucosa: a review.

Authors:  C Russell Chen; Carolina Kachramanoglou; Daqing Li; Peter Andrews; David Choi
Journal:  J Neurol Surg B Skull Base       Date:  2014-06-26

6.  Safety and efficacy of superior turbinate biopsies as a source of olfactory epithelium appropriate for morphological analysis.

Authors:  Ellen Cristine Duarte Garcia; Ana Carolina Rossaneis; Alexandre Salvatore Pipino; Gustavo Vasconcelos Gomes; Fábio de Rezende Pinna; Richard Louis Voegels; Richard L Doty; Waldiceu Aparecido Verri; Marco Aurélio Fornazieri
Journal:  Eur Arch Otorhinolaryngol       Date:  2019-11-16       Impact factor: 2.503

7.  Neurofilament profile in olfactory mucosa of patients with a clinical diagnosis of Alzheimer's disease.

Authors:  S Kaakkola; J Palo; H Malmberg; R Sulkava; I Virtanen
Journal:  Virchows Arch       Date:  1994       Impact factor: 4.064

8.  Examination and classification of human olfactory mucosa in patients with clinical olfactory disturbances.

Authors:  M Yamagishi; S Hasegawa; Y Nakano
Journal:  Arch Otorhinolaryngol       Date:  1988

9.  Human olfactory neurons respond to odor stimuli with an increase in cytoplasmic Ca2+.

Authors:  D Restrepo; Y Okada; J H Teeter; L D Lowry; B Cowart; J G Brand
Journal:  Biophys J       Date:  1993-06       Impact factor: 4.033

10.  Continuous culture of neuronal cells from adult human olfactory epithelium.

Authors:  B Wolozin; T Sunderland; B B Zheng; J Resau; B Dufy; J Barker; R Swerdlow; H Coon
Journal:  J Mol Neurosci       Date:  1992       Impact factor: 3.444
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