Literature DB >> 7072716

Chromosomal localization of the human placental lactogen-growth hormone gene cluster to 17q22-24.

M E Harper, H A Barrera-Saldaña, G F Saunders.   

Abstract

Recombinant plasmid HCS-pBR322 containing a 550-base-pair (bp) insert of cDNA to human placental lactogen (hPL) mRNA was 3H-labeled by nick translation and hybridized in situ to human chromosome preparations in the presence of 10% dextran sulfate. A high percentage of cells (80%) were found to exhibit label on the distal end of the long arm of chromosome 17. Silver grains on this region constituted 25.5% of all labeled sites, allowing assignment of the hPL and growth hormone (hGH) genes, which have over 90% nucleotide homology in their coding sequences, to 17q22-24. A gene copy number experiment showed that both genes are present in approximately three copies per haploid genome.

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Year:  1982        PMID： 7072716      PMCID： PMC1685277     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  24 in total

1.  Recovery of DNA from gels.

Authors:  H O Smith
Journal:  Methods Enzymol       Date:  1980       Impact factor: 1.600

2.  Construction and analysis of recombinant DNA for human chorionic somatomammotropin.

Authors:  J Shine; P H Seeburg; J A Martial; J D Baxter; H M Goodman
Journal:  Nature       Date:  1977-12-08       Impact factor: 49.962

3.  The isolation and characterization of linked delta- and beta-globin genes from a cloned library of human DNA.

Authors:  R M Lawn; E F Fritsch; R C Parker; G Blake; T Maniatis
Journal:  Cell       Date:  1978-12       Impact factor: 41.582

4.  Localisation of the G gamma-, A gamma-, delta- and beta-globin genes on the short arm of human chromosome 11.

Authors:  A J Jeffreys; I W Craig; U Francke
Journal:  Nature       Date:  1979-10-18       Impact factor: 49.962

5.  Structure of genes for human growth hormone and chorionic somatomammotropin.

Authors:  J C Fiddes; P H Seeburg; F M DeNoto; R A Hallewell; J D Baxter; H M Goodman
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

6.  The ovalbumin gene: alleles created by mutations in the intervening sequences of the natural gene.

Authors:  E C Lai; S L Woo; A Dugaiczyk; B W O'Malley
Journal:  Cell       Date:  1979-01       Impact factor: 41.582

7.  Genes coding for histone proteins in man are located on the distal end of the long arm of chromosome 7.

Authors:  M E Chandler; L H Kedes; R H Cohn; J J Yunis
Journal:  Science       Date:  1979-08-31       Impact factor: 47.728

8.  Human placental lactogen mRNA and its structural genes during pregnancy: quantitation with a complementary DNA.

Authors:  D McWilliams; R C Callahan; I Boime
Journal:  Proc Natl Acad Sci U S A       Date:  1977-03       Impact factor: 11.205

9.  The prolactin gene is located on chromosome 6 in humans.

Authors:  D Owerbach; W J Rutter; N E Cooke; J A Martial; T B Shows
Journal:  Science       Date:  1981-05-15       Impact factor: 47.728

10.  The status of the gene map of the human chromosomes.

Authors:  V A McKusick; F H Ruddle
Journal:  Science       Date:  1977-04-22       Impact factor: 47.728
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  33 in total

1.  Dissociation of cytotoxicity and DNA cleavage activity induced by topoisomerase II-reactive intercalating agents in hamster-human somatic cell hybrids.

Authors:  B S Glisson; A M Killary; P Merta; W E Ross; J Siciliano; M J Siciliano
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

2.  Localization of the human chromosome 5q genes Gabra-1, Gabrg-2, Il-4, Il-5, and Irf-1 on mouse chromosome 11.

Authors:  M S Buckwalter; A C Lossie; L M Scarlett; S A Camper
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 3.  Mouse chromosome 13.

Authors:  M J Justice; D A Stephenson
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

4.  Phosphoproteomic analysis of the human pituitary.

Authors:  Sarka Beranova-Giorgianni; Yingxin Zhao; Dominic M Desiderio; Francesco Giorgianni
Journal:  Pituitary       Date:  2006       Impact factor: 4.107

Review 5.  Mouse chromosome 13.

Authors:  M J Justice; D A Stephenson
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

Review 6.  Mouse chromosome 11.

Authors:  A M Buchberg; J J Moskow; M S Buckwalter; S A Camper
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

7.  Coding potential of transfected human placental lactogen genes.

Authors:  D Reséndez-Pérez; R Ramírez-Solís; A Varela-Echavarría; H G Martínez-Rodríguez; H A Barrera-Saldaña
Journal:  Nucleic Acids Res       Date:  1990-08-25       Impact factor: 16.971

8.  The human salivary protein complex (SPC): a large block of related genes.

Authors:  P A Goodman; P L Yu; E A Azen; R C Karn
Journal:  Am J Hum Genet       Date:  1985-07       Impact factor: 11.025

9.  Structure of the human gene encoding the invariant gamma-chain of class II histocompatibility antigens.

Authors:  J Kudo; L Y Chao; F Narni; G F Saunders
Journal:  Nucleic Acids Res       Date:  1985-12-20       Impact factor: 16.971

10.  Human type I procollagen genes are located on different chromosomes.

Authors:  C Huerre; C Junien; D Weil; M L Chu; M Morabito; N Van Cong; J C Myers; C Foubert; M S Gross; D J Prockop; A Boué; J C Kaplan; A de la Chapelle; F Ramirez
Journal:  Proc Natl Acad Sci U S A       Date:  1982-11       Impact factor: 11.205
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