Literature DB >> 7060531

Differential regulation by glucocorticoids of proopiomelanocortin mRNA levels in the anterior and intermediate lobes of the rat pituitary.

B S Schachter, L K Johnson, J D Baxter, J L Roberts.   

Abstract

Glucocorticoids negatively regulate de novo synthesis of proopiomelanocortin (POMC) and the steady state POMC mRNA levels in the rat pituitary anterior lobe. The POMC system of the intermediate lobe is far less sensitive to alterations in circulating glucocorticoid levels. Possible mechanisms for this differential regulation of POMC gene expression in the two tissues are discussed.

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Year:  1982        PMID： 7060531     DOI： 10.1210/endo-110-4-1442

Source DB:  PubMed          Journal:  Endocrinology        ISSN： 0013-7227            Impact factor:   4.736


  10 in total

1.  Quantitative non-radioactive in situ hybridization. Model studies and studies on pituitary proopiomelanocortin cells after adrenalectomy.

Authors:  L I Larsson; B Traasdahl; D M Hougaard
Journal:  Histochemistry       Date:  1991

2.  A possible role for intermediate lobe peptides in the pathogenesis of idiopathic aldosteronism.

Authors:  P J Mulrow
Journal:  Trans Am Clin Climatol Assoc       Date:  1984

3.  Pituitary-like proopiomelanocortin transcripts in human Leydig cell tumors.

Authors:  Y de Keyzer; F Lenne; J F Massias; D Vieau; J P Luton; A Kahn; X Bertagna
Journal:  J Clin Invest       Date:  1990-09       Impact factor: 14.808

4.  Complete nucleotide sequence of the human corticotropin-beta-lipotropin precursor gene.

Authors:  H Takahashi; Y Hakamata; Y Watanabe; R Kikuno; T Miyata; S Numa
Journal:  Nucleic Acids Res       Date:  1983-10-11       Impact factor: 16.971

5.  Estradiol feedback effects on the alpha-subunit mRNA in the sheep pituitary gland: correlation with serum and pituitary luteinizing hormone concentrations.

Authors:  T Landefeld; J Kepa; F Karsch
Journal:  Proc Natl Acad Sci U S A       Date:  1984-03       Impact factor: 11.205

6.  Strain-specific steroidal control of pituitary function.

Authors:  Sang-Nam Lee; Bonnie Peng; Roxane Desjardins; John E Pintar; Robert Day; Iris Lindberg
Journal:  J Endocrinol       Date:  2007-03       Impact factor: 4.286

7.  Regulation of the pro-opiomelanocortin mRNA levels in rat pituitary by dopaminergic compounds.

Authors:  C L Chen; F T Dionne; J L Roberts
Journal:  Proc Natl Acad Sci U S A       Date:  1983-04       Impact factor: 11.205

8.  Evaluation of proopiomelanocortin mRNA in the peripheral blood from patients with Cushing's syndrome of different origin.

Authors:  S Bondioni; G Mantovani; N Polentarutti; B Ambrosi; P Loli; E Peverelli; A G Lania; P Beck-Peccoz; A Spada
Journal:  J Endocrinol Invest       Date:  2007-11       Impact factor: 4.256

9.  Detection of proopiomelanocortin mRNA by in situ hybridization with an oligonucleotide probe.

Authors:  M E Lewis; T G Sherman; S Burke; H Akil; L G Davis; R Arentzen; S J Watson
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

10.  Glucocorticoids regulate proopiomelanocortin gene expression in vivo at the levels of transcription and secretion.

Authors:  N C Birnberg; J C Lissitzky; M Hinman; E Herbert
Journal:  Proc Natl Acad Sci U S A       Date:  1983-11       Impact factor: 11.205
  10 in total

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