Literature DB >> 6314261

Complete nucleotide sequence of the human corticotropin-beta-lipotropin precursor gene.

H Takahashi, Y Hakamata, Y Watanabe, R Kikuno, T Miyata, S Numa.   

Abstract

The nucleotide sequence of an 8658-base-pair human genomic DNA segment containing the entire corticotropin-beta-lipotropin precursor gene has been determined, and some sequence features of the gene and its flanking regions have been analysed. The gene is composed of 7665 base pairs including two introns of 3708 and 2886 base pairs. Comparison of the 5'-flanking sequences of the human, bovine and mouse corticotropin-beta-lipotropin precursor genes reveals the presence of a highly conserved region, which contains sequences of 14-15 base pairs homologous with sequences located upstream of the mRNA start site of other glucocorticoid-regulated genes.

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Year:  1983        PMID： 6314261      PMCID： PMC326418          DOI： 10.1093/nar/11.19.6847

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  45 in total

1.  Effects of steroid hormones on the level of corticotropin messenger RNA activity in cultured mouse-pituitary-tumor cells.

Authors:  M Nakamura; S Nakanishi; S Sueoka; H Imura; S Numa
Journal:  Eur J Biochem       Date:  1978-05

2.  Dexamethasone-mediated induction of mouse mammary tumor virus RNA: a system for studying glucocorticoid action.

Authors:  G M Ringold; K R Yamamoto; G M Tomkins; M Bishop; H E Varmus
Journal:  Cell       Date:  1975-11       Impact factor: 41.582

3.  Regulation of growth hormone messenger RNA by thyroid and glucocorticoid hormones.

Authors:  J A Martial; J D Baxter; H M Goodman; P H Seeburg
Journal:  Proc Natl Acad Sci U S A       Date:  1977-05       Impact factor: 11.205

4.  Pregrowth hormone messenger RNA: glucocorticoid induction and identification in rat pituitary cells.

Authors:  R J Tushinski; P M Sussman; L Y Yu; F C Bancroft
Journal:  Proc Natl Acad Sci U S A       Date:  1977-06       Impact factor: 11.205

5.  A catenated DNA molecule as an intermediate in the replication of the resistance transfer factor R6K in Escherichia coli.

Authors:  Y M Kupersztoch; D R Helinski
Journal:  Biochem Biophys Res Commun       Date:  1973-10-15       Impact factor: 3.575

6.  A catalogue of splice junction sequences.

Authors:  S M Mount
Journal:  Nucleic Acids Res       Date:  1982-01-22       Impact factor: 16.971

7.  Glucocorticoid effect on the level of corticotropin messenger RNA activity in rat pituitary.

Authors:  S Nakanishi; T Kita; S Taii; H Imura; S Numa
Journal:  Proc Natl Acad Sci U S A       Date:  1977-08       Impact factor: 11.205

8.  Mammary tumor virus induction by glucocorticoids. Characterization of specific transcriptional regulation.

Authors:  W P Parks; J C Ransom; H A Young; E M Scolnick
Journal:  J Biol Chem       Date:  1975-05-10       Impact factor: 5.157

9.  DNA sequences required for transcription in vivo of the human corticotropin-beta-lipotropin precursor gene.

Authors:  M Mishina; T Kurosaki; T Yamamoto; M Notake; M Masu; S Numa
Journal:  EMBO J       Date:  1982       Impact factor: 11.598

10.  Production of both prolactin and growth hormone by clonal strains of rat pituitary tumor cells. Differential effects of hydrocortisone and tissue extracts.

Authors:  A H Tashjian; F C Bancroft; L Levine
Journal:  J Cell Biol       Date:  1970-10       Impact factor: 10.539
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  18 in total

1.  Glycoprotein hormone genes are expressed in clinically nonfunctioning pituitary adenomas.

Authors:  J L Jameson; A Klibanski; P M Black; N T Zervas; C M Lindell; D W Hsu; E C Ridgway; J F Habener
Journal:  J Clin Invest       Date:  1987-11       Impact factor: 14.808

2.  Pituitary development and physiology.

Authors:  Clement C Cheung; Robert H Lustig
Journal:  Pituitary       Date:  2007       Impact factor: 4.107

3.  The 5' splice site: phylogenetic evolution and variable geometry of association with U1RNA.

Authors:  M Jacob; H Gallinaro
Journal:  Nucleic Acids Res       Date:  1989-03-25       Impact factor: 16.971

4.  Pituitary-like proopiomelanocortin transcripts in human Leydig cell tumors.

Authors:  Y de Keyzer; F Lenne; J F Massias; D Vieau; J P Luton; A Kahn; X Bertagna
Journal:  J Clin Invest       Date:  1990-09       Impact factor: 14.808

5.  Nucleotide sequence of a cloned cDNA for proopiomelanocortin precursor of chum salmon, Onchorynchus keta.

Authors:  G I Soma; N Kitahara; T Nishizawa; H Nanami; C Kotake; H Okazaki; T Andoh
Journal:  Nucleic Acids Res       Date:  1984-11-12       Impact factor: 16.971

Review 6.  POMC: The Physiological Power of Hormone Processing.

Authors:  Erika Harno; Thanuja Gali Ramamoorthy; Anthony P Coll; Anne White
Journal:  Physiol Rev       Date:  2018-10-01       Impact factor: 37.312

Review 7.  The role of intracellular messengers in adrenocorticotropin secretion in vitro.

Authors:  M S King; A J Baertschi
Journal:  Experientia       Date:  1990-01-15

8.  Evidence for higher rates of nucleotide substitution in rodents than in man.

Authors:  C I Wu; W H Li
Journal:  Proc Natl Acad Sci U S A       Date:  1985-03       Impact factor: 11.205

9.  Human pituitary contains dual cathepsin L and prohormone convertase processing pathway components involved in converting POMC into the peptide hormones ACTH, alpha-MSH, and beta-endorphin.

Authors:  Vivian Hook; Lydiane Funkelstein; Thomas Toneff; Charles Mosier; Shin-Rong Hwang
Journal:  Endocrine       Date:  2009-04-03       Impact factor: 3.633

10.  Carney complex, a familial multiple neoplasia and lentiginosis syndrome. Analysis of 11 kindreds and linkage to the short arm of chromosome 2.

Authors:  C A Stratakis; J A Carney; J P Lin; D A Papanicolaou; M Karl; D L Kastner; E Pras; G P Chrousos
Journal:  J Clin Invest       Date:  1996-02-01       Impact factor: 14.808
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