Literature DB >> 7058347

In vivo mapping of local cerebral blood flow by xenon-enhanced computed tomography.

D Gur, W F Good, S K Wolfson, H Yonas, L Shabason.   

Abstract

A noninvasive technique has been developed to measure and display local cerebral blood flow (LCBF) in vivo. In this procedure, nonradioactive xenon gas is inhaled and the temporal changes in radiographic enhancement produced by the inhalation are measured by sequential computerized tomography. The time-dependent xenon concentrations in various anatomical units in the brain are used to derive both the local partition coefficient and the LCBF. Functional mapping of blood flow with excellent anatomical specificity has been obtained in the baboon brain. The response of LCBF to stimuli such as changes in carbon dioxide concentrations as well as the variability in LCBF in normal and diseased tissue can be easily demonstrated. This method is applicable to the study of human physiology and pathologic blood flow alterations.

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Year:  1982        PMID： 7058347     DOI： 10.1126/science.7058347

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  28 in total

1.  Xenon-inhalation computed tomography for noninvasive quantitative measurement of tissue blood flow in pancreatic tumor.

Authors:  Masaru Kubota; Takamichi Murakami; Hiroaki Nagano; Hidetoshi Eguchi; Shigeru Marubashi; Shogo Kobayashi; Hiroshi Wada; Masahiro Tanemura; Keizo Dono; Shoji Nakamori; Masato Sakon; Morito Monden; Masaki Mori; Yuichiro Doki
Journal:  Dig Dis Sci       Date:  2011-09-28       Impact factor: 3.199

2.  Magnetic resonance imaging of perfusion using spin inversion of arterial water.

Authors:  D S Williams; J A Detre; J S Leigh; A P Koretsky
Journal:  Proc Natl Acad Sci U S A       Date:  1992-01-01       Impact factor: 11.205

3.  Complications of preoperative balloon test occlusion of the internal carotid arteries: experience in 300 cases.

Authors:  R W Tarr; C A Jungreis; J A Horton; S Pentheny; L N Sekhar; C Sen; I P Janecka; H Yonas
Journal:  Skull Base Surg       Date:  1991

4.  Xenon-enhanced cerebral blood flow at 28% xenon provides uniquely safe access to quantitative, clinically useful cerebral blood flow information: a multicenter study.

Authors:  A P Carlson; A M Brown; E Zager; K Uchino; M P Marks; C Robertson; G P Sinson; A Marmarou; H Yonas
Journal:  AJNR Am J Neuroradiol       Date:  2011-06-23       Impact factor: 3.825

Review 5.  Arterial spin labeling for the measurement of cerebral perfusion and angiography.

Authors:  Peter Jezzard; Michael A Chappell; Thomas W Okell
Journal:  J Cereb Blood Flow Metab       Date:  2017-11-23       Impact factor: 6.200

6.  Quantitative magnetic resonance imaging of human brain perfusion at 1.5 T using steady-state inversion of arterial water.

Authors:  D A Roberts; J A Detre; L Bolinger; E K Insko; J S Leigh
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-04       Impact factor: 11.205

7.  Perfusion Characteristics in Chronic Cerebrovascular Insufficiency : An Anatomically and Clinically Oriented XeCT Analysis of Cerebrovascular Atherosclerotic Disease.

Authors:  Gerrit Alexander Schubert; Marcel Seiz; Marcus Czabanka; Claudius Thomé
Journal:  Transl Stroke Res       Date:  2011-10-04       Impact factor: 6.829

8.  Correlation between hepatic blood flow and liver function in alcoholic liver cirrhosis.

Authors:  Hideaki Takahashi; Ryuta Shigefuku; Yoshihito Yoshida; Hiroki Ikeda; Kotaro Matsunaga; Nobuyuki Matsumoto; Chiaki Okuse; Shigeru Sase; Fumio Itoh; Michihiro Suzuki
Journal:  World J Gastroenterol       Date:  2014-12-07       Impact factor: 5.742

9.  Proton therapy reduces the likelihood of high-grade radiation-induced lymphopenia in glioblastoma patients: phase II randomized study of protons vs photons.

Authors:  Radhe Mohan; Amy Y Liu; Paul D Brown; Anita Mahajan; Jeffrey Dinh; Caroline Chung; Sarah McAvoy; Mary Frances McAleer; Steven H Lin; Jing Li; Amol J Ghia; Cong Zhu; Erik P Sulman; John F de Groot; Amy B Heimberger; Susan L McGovern; Clemens Grassberger; Helen Shih; Susannah Ellsworth; David R Grosshans
Journal:  Neuro Oncol       Date:  2021-02-25       Impact factor: 12.300

10.  Improving dynamic susceptibility contrast MRI measurement of quantitative cerebral blood flow using corrections for partial volume and nonlinear contrast relaxivity: A xenon computed tomographic comparative study.

Authors:  Greg Zaharchuk; Roland Bammer; Matus Straka; Rexford D Newbould; Jarrett Rosenberg; Jean-Marc Olivot; Michael Mlynash; Maarten G Lansberg; Neil E Schwartz; Michael M Marks; Gregory W Albers; Michael E Moseley
Journal:  J Magn Reson Imaging       Date:  2009-10       Impact factor: 4.813
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