Literature DB >> 7057791

Normal sister-chromatid exchanges in oral contraceptive users.

B Husum, H C Wulf, E Niebuhr.   

Abstract

Sister-chromatid exchanges in peripheral lymphocytes were examined in 115 healthy women, aged 15-43 years. 63 women were on no medication at all, and 52 women used oral contraceptives. 30 metaphases from each culture were scored for SCE. In accord with previous studies, cigarette smoking increased SCE. The use of oral contraceptives had no influence on SCE on non-smoking and in cigarette-smoking women. Thus the results did not indicate any potential mutagenic effect of oral contraceptives.

Entities:  

Keywords:  Behavior; Clinical Research; Contraception; Contraceptive Methods--side effects; Examinations And Diagnoses; Family Planning; Laboratory Examinations And Diagnoses; Laboratory Procedures; Oral Contraceptives--side effects; Research Methodology; Smoking

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Substances:

Year:  1982        PMID: 7057791     DOI: 10.1016/0165-7992(82)90023-9

Source DB:  PubMed          Journal:  Mutat Res        ISSN: 0027-5107            Impact factor:   2.433


  3 in total

Review 1.  The risks of handling cytotoxic drugs. I. Methods of testing exposure.

Authors:  G P Kaijser; W J Underberg; J H Beijnen
Journal:  Pharm Weekbl Sci       Date:  1990-12-14

2.  Steroid hormones enhanced sister-chromatid exchange in cultured CHO cells.

Authors:  T S Kochhar
Journal:  Experientia       Date:  1988-01-15

3.  Urine mutagenicity, chromosomal abnormalities and sister chromatid exchanges in lymphocytes of nurses handling cytostatic drugs.

Authors:  I Stucker; A Hirsch; T Doloy; I Bastie-Sigeac; D Hemon
Journal:  Int Arch Occup Environ Health       Date:  1986       Impact factor: 3.015

  3 in total

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