Literature DB >> 3350124

Steroid hormones enhanced sister-chromatid exchange in cultured CHO cells.

T S Kochhar1.   

Abstract

The influence of steroid hormones on the induction of sister-chromatid exchange (SCE) in cultured CHO cells was studied. It was observed that estradiol-17 beta, estriol, estrone and ethynyl estradiol treatments enhanced SCE rates compared to the controls. Overall, these compounds produced a dose response effect. The importance of a detailed study on the long-term genetic effects of steroids on mammalian cells is emphasized.

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Year:  1988        PMID： 3350124     DOI： 10.1007/bf01960247

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  11 in total

1.  Chromosome aberrations and sister chromatid exchanges in Chinese hamster cells exposed to various chemicals.

Authors:  S Abe; M Sasaki
Journal:  J Natl Cancer Inst       Date:  1977-06       Impact factor: 13.506

2.  Structural specificity of estrogens in the induction of mitotic chromatid non-disjunction in HeLa cells.

Authors:  P N Rao; J Engelberg
Journal:  Exp Cell Res       Date:  1967-10       Impact factor: 3.905

3.  Sister-chromatid exchanges in oral contraceptive users.

Authors:  P B Murthy; K Prema
Journal:  Mutat Res       Date:  1979-10       Impact factor: 2.433

Review 4.  Cytological effects of the oral contraceptive.

Authors:  N Bishun; N Smith; D Williams; J Mills
Journal:  Mutat Res       Date:  1976       Impact factor: 2.433

5.  Normal sister-chromatid exchanges in oral contraceptive users.

Authors:  B Husum; H C Wulf; E Niebuhr
Journal:  Mutat Res       Date:  1982-02       Impact factor: 2.433

6.  The induction of sister-chromatid exchanges in Chinese hamster ovary cells by prolonged exposure to 2-acetylaminofluorene and S-9 mix.

Authors:  S Takehisa; S Wolff
Journal:  Mutat Res       Date:  1978-09       Impact factor: 2.433

7.  Chromosome breakage studies in lymphocytes from normal women, pregnant women, and women taking oral contraceptives.

Authors:  L G Littlefield; W E Lever; F L Miller; K O Goh
Journal:  Am J Obstet Gynecol       Date:  1975-04-01       Impact factor: 8.661

8.  Inducibility of chromosome aberrations by steroid hormones in cultured Chinese hamster ovary cells.

Authors:  T S Kochhar
Journal:  Toxicol Lett       Date:  1985-12       Impact factor: 4.372

9.  Factors involved in differential Giemsa-staining of sister chromatids.

Authors:  K Goto; S Maeda; Y Kano; T Sugiyama
Journal:  Chromosoma       Date:  1978-05-16       Impact factor: 4.316

10.  Further studies on sister-chromatid exchange frequency in users of hormonal contraceptives.

Authors:  P B Murthy; K Prema
Journal:  Mutat Res       Date:  1983-03       Impact factor: 2.433
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  2 in total

1.  Enhanced production of micronuclei by hexavalent chromium in cultured CHO cells.

Authors:  W R Howard; S A Hoffman; T S Kochhar
Journal:  Bull Environ Contam Toxicol       Date:  1992-10       Impact factor: 2.151

2.  In situ demonstration of the activity of 3 beta-hydroxysteroid dehydrogenase on steroid hormone secreting cells within the paraaortic lymph nodes of golden hamster.

Authors:  K Tohya; R Sugata; S Toda; M Kimura
Journal:  Experientia       Date:  1989-08-15
  2 in total

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